Swift induction of human spinal lower motor neurons and robust ALS cell screening via single-cell imaging
Swift induction of human spinal lower motor neurons and robust ALS cell screening via single-cell imaging Selena Setsu, Satoru Morimoto, Shiho Nakamura, Fumiko Ozawa, Kagistia Hana Utami, Ayumi Nishiyama, Naoki Suzuki, Masashi Aoki, Yukio Takeshita, Yukihide Tomari, Hideyuki Okano. Stem Cell Reports. 2025 Jan 14. https://doi.org/10.1016/j.stemcr.2024.11.007 Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease marked by motor neuron degeneration. While induced pluripotent stem cells (iPSCs) have emerged as a powerful tool for drug screening and studying ALS pathology, challenges…