MaxOne

New Therapeutic Target in the Fight Against ALS

Scientists uncover a new protein in a pathway for neurotoxicity and cell death A new study published in Nature takes us one step forward in understanding the key mechanisms behind neurodegenerative diseases. With the urgent need for human cellular models to study such pathologies, scientists have developed a new 2D cell culture model with features mirroring those of human brains, with the support from MaxWell Biosystems’ high-density Microelectrode arrays (HD-MEAs). Delving deeper into the effects of the abnormal accumulation of TAR DNA-binding protein…

Read More

Interview with Brett Kagan – Cortical Labs

MxW Interview with Brett Kagan Cortical Labs, Melbourne, Australia Recently, we had the pleasure of having Dr. Brett Kagan from Cortical Labs visiting us here in the MaxWell Biosystems HQ in Zurich and hosting an exciting seminar on their recent work and progress. Dr. Brett Kagan’s latest work on “training neural networks to play Pong using HD-MEAs”, published in Neuron (Kagan et al, Neuron, 2022), became viral last year, and we had the opportunity to learn more about this study,…

Read More

Join the Conversation with Prof. Kenneth S. Kosik and Dr. Tal Sharf

Interview and Featured Publication Join the Conversation with Prof. Kenneth Kosik and Dr. Tal Sharf Recently, Dr. Tal Sharf, Prof. Kenneth S. Kosik and colleagues released a pre-print on their novel work entitled, “Human brain organoid networks”, currently under revision. Aiming to explore the physiological behavior of neuronal circuits within organoids, this work demonstrates that human brain organoids have self-organized neuronal assemblies of sufficient size, cellular orientation, and functional connectivity to co-activate and generate field potentials from their collective transmembrane…

Read More

HD-MEAs play a role in the functional characterization of human iPSC-derived dopaminergic neurons

Maria Sundberg from the Boston Children’s Hospital, Harvard Medical School, and colleagues, recently reported in Nature Communications a study on the reciprocal copy number variations (CNVs) of 16p11.2 gene region, associated with a wide spectrum of neuropsychiatric and neurodevelopmental disorders. For the functional analysis of the developing iPSC-derived dopaminergic (DA) neuron network, complementary-metal-oxide-semiconductor (CMOS)-based high-density microelectrode arrays (HD-MEAs), MaxOne System by MaxWell Biosystems was extensively used. 16p.11.2 Reciprocal copy number variations (CNVs) in neuropsychiatric disorders 16p.11.2 CNVs have been implicated in…

Read More

Retina study utilizing HD-MEAs (MaxOne) selected as “Best of Neuron”

The paper by K. Yonehara*, M. Fiscella*, A. Drinnenberg*, et al. entitled “Congenital Nystagmus Gene FRMD7 is necessary for establishing a neuronal circuit asymmetry for direction selectivity” was chosen for the “Best of Neuron” selection 2015-2016. “Best of Neuron“ includes ground-breaking neuroscience research published in Neuron and is a collection of editors’ and readers’ favorites. MaxWell Biosystems HD-MEA core technology was used in this study, to characterize the disease phenotype discovered in the FRMD7 mutant retina. Mutation in the FRMD7 gene is linked to the…

Read More
Contact Us






Albisriederstrasse 253
8047 Zurich, Switzerland
+41 44 244 24 24
Schedule a call
info@mxwbio.com
Subscribe to our Newsletter