論文

Publications

 


Selected Publications

Mueller2015

High-resolution CMOS MEA platform to study neurons at subcellular, cellular, and network levels

Presenting measurements of neuronal preparations with a novel CMOS-based microelectrode array at high-spatiotemporal-resolution on subcellular, cellular, and network level.

J. Müller, M. Ballini, P. Livi, Y. Chen, M. Radivojevic, A. Shadmani, V. Viswam, I. L. Jones, M. Fiscella, R. Diggelmann, A. Stettler, U. Frey, D. J. Bakkum, and A. Hierlemann, “High-resolution CMOS MEA platform to study neurons at subcellular, cellular, and network levels,” Lab Chip, vol. 15, no. 13, pp. 2767–2780, May 2015.

Obien2014

Revealing Neuronal Function through Microelectrode Array Recordings

Reviewing the current understanding of microelectrode signals and the techniques for analyzing them, with focus on the ongoing advancements in microelectrode technology (in vivo and in vitro) and recent advanced microelectrode array measurement methods that facilitate the understanding of single neurons and network function.

M. E. J. Obien, K. Deligkaris, T. Bullmann, D. J. Bakkum, and U. Frey, “Revealing Neuronal Function through Microelectrode Array Recordings,” Front. Neurosci., 8:423, Jan 2015.

Ballini2014

A 1024-Channel CMOS Microelectrode Array With 26,400 Electrodes for Recording and Stimulation of Electrogenic Cells In Vitro

A high-resolution CMOS-based microelectrode array featuring 1,024 low-noise readout channels, 26,400 electrodes at a density of 3,265 electrodes per mm2, including on-chip 10bit ADCs and consuming only 75 mW.

M. Ballini, J. Muller, P. Livi, Y. Chen, U. Frey, A. Stettler, A. Shadmani, V. Viswam, I. L. Jones, D. Jackel, M. Radivojevic, M. K. Lewandowska, W. Gong, M. Fiscella, D. J. Bakkum, F. Heer, and A. Hierlemann, “A 1024-Channel CMOS Microelectrode Array With 26,400 Electrodes for Recording and Stimulation of Electrogenic Cells In Vitro,” IEEE Journal of Solid-State Circuits, vol. 49, no. 11, pp. 2705-2719, 2014.

Bakkum2013ncomm

Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites

Demonstrating a method to electrically visualize action potential propagation on axons and revealing
large variations in velocity.

D. J. Bakkum, U. Frey, M. Radivojevic, T. L. Russell, J. Muller, M. Fiscella, H. Takahashi, and A. Hierlemann, “Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites,” Nature Communications, 4:2181, Jul 2013.

Frey08BioSensors

Microelectronic System for High-Resolution Mapping of Extracellular Electric Fields Applied to Brain Slices

Recording and modeling extracellular action potentials of Purkinje cells at subcellular resolution.

U. Frey, U. Egert, F. Heer, S. Hafizovic, and A. Hierlemann, “Microelectronic System for High-Resolution Mapping of Extracellular Electric Fields Applied to Brain Slices,” Biosensors and Bioelectronics, vol. 24, no. 7, pp. 2191-2198, 2009.

SanchezBustamante07NRC

Modulation of Cardiomyocyte Electrical Properties Using Regulated Bone Morphogenetic Protein-2 Expression

Controlling BMP-2 expression to modulate the electrophysiological properties of cardiomyocytes using an HD-MEA for detailed monitoring.

C. D. Sanchez-Bustamante, U. Frey, J. M. Kelm, A. Hierlemann, and M. Fussenegger,
“Modulation of Cardiomyocyte Electrical Properties Using Regulated Bone Morphogenetic Protein-2 Expression,” Tissue Engineering Part A, vol. 14, no. 12, pp. 1969-1988, 2008.


All Publications

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32 entries « 1 of 2 »
1. Sharf Tal; Molen, Tjitse; Glasauer Stella; Guzman Elmer; Buccino Alessio; Luna Gabriel; Cheng Zhuowei; Audouard Morgane; Ranasinghe Kamalini; Kudo Kiwamu; Nagarajan Srikantan; Tovar Kenneth; Petzold Linda; Hierlemann Andreas; Hansma Paul; ; Kosik, Kenneth; : Functional neuronal circuitry and oscillatory dynamics in human brain organoids. In: Nature Communications, 2022. (Type: Journal Article | Abstract | Links | BibTeX)
2. Sommer Daniel ; Rajkumar, Sandeep; Seidel Mira; Aly Amr; Ludolph Albert; Ho Ritchie; Boeckers Tobias; Catanese Alberto. : Aging-Dependent Altered Transcriptional Programs Underlie Activity Impairments in Human C9orf72-Mutant Motor Neurons. In: Frontiers in Molecular Neuroscience, 2022. (Type: Journal Article | Abstract | Links | BibTeX)
3. Sato Yuya; Yamamoto, Hideaki; Kato Hideyuki; Tanii Takashi; Sato Shigeo; Hirano-Iwata Ayumi : Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks. In: 2022. (Type: Journal Article | Abstract | Links | BibTeX)
4. Duru Jens; Küchler, Joël; Ihle Stephan Forró Csaba; Bernardi Aeneas; Girardin Sophie; Hengsteler Julian; Wheeler Stephen; János; Ruff Tobias; J ; Vörös: Engineered Biological Neural Networks on High Density CMOS Microelectrode Arrays. In: 2022. (Type: Journal Article | Abstract | Links | BibTeX)
5. Xue, Xiaohan ; Buccino, Alessio Paolo ; Kumar, Sreedhar Saseendran ; Hierlemann, Andreas ; Bartram, Julian : Inferring monosynaptic connections from paired dendritic spine Ca2+ imaging and large-scale recording of extracellular spiking. In: bioRxiv, 2022. (Type: Journal Article | Abstract | Links | BibTeX)
6. McSweeney, Danny; Gabriel, Rafael; Jin, Kang; Pang, Zhiping P; Aronow, Bruce; Pak, ChangHui: Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons. In: BioRxiv, 2022. (Type: Journal Article | Abstract | Links | BibTeX)
7. Hruska-Plochan, Marian; Betz, Katharina M; Ronchi, Silvia; Wiersma, Vera I; Maniecka, Zuzanna; Hock, Eva-Maria; Laferriere, Florent; Sahadevan, Sonu; Hoop, Vanessa; Delvendahl, Igor; Panatta, Martina; van der Bourg, Alexander; Bohaciakova, Dasa; Frontzek, Karl; Aguzzi, Adriano; Lashley, Tammaryn; Robinson, Mark D; Karayannis, Theofanis; Mueller, Martin; Hierlemann, Andreas; Polymenidou, Magdalini: Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD. In: BioRxiv, 2021. (Type: Journal Article | Abstract | Links | BibTeX)
8. Sharf, Tal; van der Molen, Tjitse; Guzman, Elmer; Glasauer, Stella M K; Luna, Gabriel; Cheng, Zhouwei; Audouard, Morgane; Ranasinghe, Kamalini G; Kudo, Kiwamu; Nagarajan, Srikantan S; Tovar, Kenneth R; Petzold, Linda R; Hansma, Paul K; Kosik, Kenneth S: Intrinsic network activity in human brain organoids. In: BioRxiv, 2021. (Type: Journal Article | Abstract | Links | BibTeX)
9. Kim, Eunhee; Jeon, Sungwoong; An, Hyun-Kyu; Mehrnoosh Kianpour, Seong-Woon Yu ; Kim, Jin-young; Rah, Jong-Cheol; Choi, Hongsoo: A magnetically actuated microrobot for targeted neural cell delivery and selective connection of neural networks. In: Science Advances, 6 (39), 2020. (Type: Journal Article | Abstract | Links | BibTeX)
10. Bandarabadi, Mojtaba; Vassalli, Anne; Tafti, Mehdi: Sleep as a default state of cortical and subcortical networks. In: Current Opinion in Physiology, 15 , pp. 60-67, 2020. (Type: Journal Article | Abstract | Links | BibTeX)
11. Masumori, Atsushi; Sinapayen, Lana; Maruyama, Norihiro; Mita, Takeshi; Bakkum, Douglas J; Frey, Urs; Takahashi, Hirokazu; Ikegami, Takashi: Neural Autopoiesis: Organizing Self-Boundaries by Stimulus Avoidance in Biological and Artificial Neural Networks. In: Artificial Life, 26 (1), pp. 130-151, 2020, ISSN: 1064-5462. (Type: Journal Article | Abstract | Links | BibTeX)
12. Obien, Marie Engelene J; Frey, Urs: Large-Scale, High-Resolution Microelectrode Arrays for Interrogation of Neurons and Networks. In: Springer, 2019. (Type: Book Chapter | Abstract | Links | BibTeX)
13. Schroter, Manuel; Girr, Monika; Boos, Julia Alicia; Renner, Magdalena; Gazorpak, Mahshid; Gong, Wei; Bartram, Julian; Muller, Jan; Hierlemann, Andreas: Mapping neuronal network dynamics in developing cerebral organoids. 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting) Reutlingen, Germany, 2018. (Type: Conference | Abstract | Links | BibTeX)
14. Radivojevic, Milos; Franke, Felix; Altermatt, Michael; Müller, Jan; Hierlemann, Andreas; Bakkum, Douglas J: Tracking individual action potentials throughout mammalian axonal arbors. In: eLife, 6 , pp. 1-23, 2017, ISSN: 2050-084X. (Type: Journal Article | Abstract | Links | BibTeX)
15. Tajima Satohiro; Mita, Takeshi; Bakkum Douglas Takahashi Hirokazu; Toyoizumi Taro J;: Locally embedded presages of global network bursts. In: National Academy of Sciences, pp. 1-6, 2017, ISSN: 0027-8424. (Type: Journal Article | Abstract | Links | BibTeX)
16. Shein-Idelson, Mark; Pammer, Lorenz; Hemberger, Mike; Laurent, Gilles: Large-scale mapping of cortical synaptic projections with extracellular electrode arrays. In: Nature Methods, 14 (9), pp. 882–889, 2017, ISSN: 1548-7091. (Type: Journal Article | Abstract | Links | BibTeX)
17. Obien, Marie Engelene J; Zorzi, Giulio; Hierlemann, Andreas: Mapping neuron cluster development based on axonal action potential propagation. The 40th Annual Meeting of the Japan Neuroscience Society Chiba, Japan, 2017. (Type: Conference | BibTeX)
18. Jäckel, David; Bakkum, Douglas J; Russell, Thomas L; Müller, Jan; Radivojevic, Milos; Frey, Urs; Franke, Felix; Hierlemann, Andreas: Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration. In: Scientific Reports, 7 (1), pp. 978, 2017, ISSN: 2045-2322. (Type: Journal Article | Abstract | Links | BibTeX)
19. Yada, Yuichiro; Mita, Takeshi; Sanada, Akihiro; Yano, Ryuichi; Kanzaki, Ryohei; Bakkum, Douglas J; Hierlemann, Andreas; Takahashi, Hirokazu: Development of neural population activity toward self-organized criticality. In: Neuroscience, 343 , pp. 55-65, 2016, ISSN: 0306-4522. (Type: Journal Article | Abstract | Links | BibTeX)
20. Deligkaris, Kosmas; Bullmann, Torsten; Frey, Urs: Extracellularly Recorded Somatic and Neuritic Signal Shapes and Classification Algorithms for High-Density Microelectrode Array Electrophysiology. In: Frontiers in Neuroscience, 10 , pp. 421, 2016, ISSN: 1662-453X. (Type: Journal Article | Abstract | Links | BibTeX)
32 entries « 1 of 2 »

Show all

2022

Functional neuronal circuitry and oscillatory dynamics in human brain organoids

Sharf Tal; Molen, Tjitse; Glasauer Stella; Guzman Elmer; Buccino Alessio; Luna Gabriel; Cheng Zhuowei; Audouard Morgane; Ranasinghe Kamalini; Kudo Kiwamu; Nagarajan Srikantan; Tovar Kenneth; Petzold Linda; Hierlemann Andreas; Hansma Paul; ; Kosik, Kenneth;

Functional neuronal circuitry and oscillatory dynamics in human brain organoids Journal Article

Nature Communications, 2022.

Abstract | Links | BibTeX | タグ: MaxOne, Neuronal Networks, Organoids

Aging-Dependent Altered Transcriptional Programs Underlie Activity Impairments in Human C9orf72-Mutant Motor Neurons

Sommer Daniel ; Rajkumar, Sandeep; Seidel Mira; Aly Amr; Ludolph Albert; Ho Ritchie; Boeckers Tobias; Catanese Alberto.

Aging-Dependent Altered Transcriptional Programs Underlie Activity Impairments in Human C9orf72-Mutant Motor Neurons Journal Article

Frontiers in Molecular Neuroscience, 2022.

Abstract | Links | BibTeX | タグ: HD-MEA, MaxOne, Neuronal Networks

Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks

Sato Yuya; Yamamoto, Hideaki; Kato Hideyuki; Tanii Takashi; Sato Shigeo; Hirano-Iwata Ayumi

Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks Journal Article

2022.

Abstract | Links | BibTeX | タグ: HD-MEA, MaxOne, Neuronal Networks

Engineered Biological Neural Networks on High Density CMOS Microelectrode Arrays

Duru Jens; Küchler, Joël; Ihle Stephan Forró Csaba; Bernardi Aeneas; Girardin Sophie; Hengsteler Julian; Wheeler Stephen; János; Ruff Tobias; J ; Vörös

Engineered Biological Neural Networks on High Density CMOS Microelectrode Arrays Journal Article

2022.

Abstract | Links | BibTeX | タグ: HD-MEA, MaxOne, Neuronal Networks

Inferring monosynaptic connections from paired dendritic spine Ca2+ imaging and large-scale recording of extracellular spiking

Xue, Xiaohan ; Buccino, Alessio Paolo ; Kumar, Sreedhar Saseendran ; Hierlemann, Andreas ; Bartram, Julian

Inferring monosynaptic connections from paired dendritic spine Ca2+ imaging and large-scale recording of extracellular spiking Journal Article

bioRxiv, 2022.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, Neuronal Networks

Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons

McSweeney, Danny; Gabriel, Rafael; Jin, Kang; Pang, Zhiping P; Aronow, Bruce; Pak, ChangHui

Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons Journal Article

BioRxiv, 2022.

Abstract | Links | BibTeX | タグ: IPSC, MaxOne, Neuronal Networks

2021

Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD

Hruska-Plochan, Marian; Betz, Katharina M; Ronchi, Silvia; Wiersma, Vera I; Maniecka, Zuzanna; Hock, Eva-Maria; Laferriere, Florent; Sahadevan, Sonu; Hoop, Vanessa; Delvendahl, Igor; Panatta, Martina; van der Bourg, Alexander; Bohaciakova, Dasa; Frontzek, Karl; Aguzzi, Adriano; Lashley, Tammaryn; Robinson, Mark D; Karayannis, Theofanis; Mueller, Martin; Hierlemann, Andreas; Polymenidou, Magdalini

Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD Journal Article

BioRxiv, 2021.

Abstract | Links | BibTeX | タグ: Inhibitory Neurons, MEA Technology, Neuronal Networks

Intrinsic network activity in human brain organoids

Sharf, Tal; van der Molen, Tjitse; Guzman, Elmer; Glasauer, Stella M K; Luna, Gabriel; Cheng, Zhouwei; Audouard, Morgane; Ranasinghe, Kamalini G; Kudo, Kiwamu; Nagarajan, Srikantan S; Tovar, Kenneth R; Petzold, Linda R; Hansma, Paul K; Kosik, Kenneth S

Intrinsic network activity in human brain organoids Journal Article

BioRxiv, 2021.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, Neuronal Networks, Organoids

2020

A magnetically actuated microrobot for targeted neural cell delivery and selective connection of neural networks

Kim, Eunhee; Jeon, Sungwoong; An, Hyun-Kyu; Mehrnoosh Kianpour, Seong-Woon Yu ; Kim, Jin-young; Rah, Jong-Cheol; Choi, Hongsoo

A magnetically actuated microrobot for targeted neural cell delivery and selective connection of neural networks Journal Article

Science Advances, 6 (39), 2020.

Abstract | Links | BibTeX | タグ: microrobot, Neuronal Networks

Sleep as a default state of cortical and subcortical networks

Bandarabadi, Mojtaba; Vassalli, Anne; Tafti, Mehdi

Sleep as a default state of cortical and subcortical networks Journal Article

Current Opinion in Physiology, 15 , pp. 60-67, 2020.

Abstract | Links | BibTeX | タグ: Neuronal Networks, Review, Sleep

Neural Autopoiesis: Organizing Self-Boundaries by Stimulus Avoidance in Biological and Artificial Neural Networks

Masumori, Atsushi; Sinapayen, Lana; Maruyama, Norihiro; Mita, Takeshi; Bakkum, Douglas J; Frey, Urs; Takahashi, Hirokazu; Ikegami, Takashi

Neural Autopoiesis: Organizing Self-Boundaries by Stimulus Avoidance in Biological and Artificial Neural Networks Journal Article

Artificial Life, 26 (1), pp. 130-151, 2020, ISSN: 1064-5462.

Abstract | Links | BibTeX | タグ: Neuronal Networks

2019

Large-Scale, High-Resolution Microelectrode Arrays for Interrogation of Neurons and Networks

Obien, Marie Engelene J; Frey, Urs

Large-Scale, High-Resolution Microelectrode Arrays for Interrogation of Neurons and Networks Book Chapter

Springer, 2019.

Abstract | Links | BibTeX | タグ: In-Vitro, Neuronal Networks

2018

Mapping neuronal network dynamics in developing cerebral organoids

Schroter, Manuel; Girr, Monika; Boos, Julia Alicia; Renner, Magdalena; Gazorpak, Mahshid; Gong, Wei; Bartram, Julian; Muller, Jan; Hierlemann, Andreas

Mapping neuronal network dynamics in developing cerebral organoids Conference

11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting) Reutlingen, Germany, 2018.

Abstract | Links | BibTeX | タグ: Neuronal Networks, Organoids

2017

Tracking individual action potentials throughout mammalian axonal arbors

Radivojevic, Milos; Franke, Felix; Altermatt, Michael; Müller, Jan; Hierlemann, Andreas; Bakkum, Douglas J

Tracking individual action potentials throughout mammalian axonal arbors Journal Article

eLife, 6 , pp. 1-23, 2017, ISSN: 2050-084X.

Abstract | Links | BibTeX | タグ: Data Analysis, ETH-CMOS-MEA, Neuronal Networks, Stimulation

Locally embedded presages of global network bursts

Tajima Satohiro; Mita, Takeshi; Bakkum Douglas Takahashi Hirokazu; Toyoizumi Taro J;

Locally embedded presages of global network bursts Journal Article

National Academy of Sciences, pp. 1-6, 2017, ISSN: 0027-8424.

Abstract | Links | BibTeX | タグ: Neuronal Networks

Large-scale mapping of cortical synaptic projections with extracellular electrode arrays

Shein-Idelson, Mark; Pammer, Lorenz; Hemberger, Mike; Laurent, Gilles

Large-scale mapping of cortical synaptic projections with extracellular electrode arrays Journal Article

Nature Methods, 14 (9), pp. 882–889, 2017, ISSN: 1548-7091.

Abstract | Links | BibTeX | タグ: Brain Slice, MaxOne, Neuronal Networks

Mapping neuron cluster development based on axonal action potential propagation

Obien, Marie Engelene J; Zorzi, Giulio; Hierlemann, Andreas

Mapping neuron cluster development based on axonal action potential propagation Conference

The 40th Annual Meeting of the Japan Neuroscience Society Chiba, Japan, 2017.

BibTeX | タグ: Action Potential, Neuronal Networks

Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration

Jäckel, David; Bakkum, Douglas J; Russell, Thomas L; Müller, Jan; Radivojevic, Milos; Frey, Urs; Franke, Felix; Hierlemann, Andreas

Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration Journal Article

Scientific Reports, 7 (1), pp. 978, 2017, ISSN: 2045-2322.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, Neuronal Networks

2016

Development of neural population activity toward self-organized criticality

Yada, Yuichiro; Mita, Takeshi; Sanada, Akihiro; Yano, Ryuichi; Kanzaki, Ryohei; Bakkum, Douglas J; Hierlemann, Andreas; Takahashi, Hirokazu

Development of neural population activity toward self-organized criticality Journal Article

Neuroscience, 343 , pp. 55-65, 2016, ISSN: 0306-4522.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, Neuronal Networks

Extracellularly Recorded Somatic and Neuritic Signal Shapes and Classification Algorithms for High-Density Microelectrode Array Electrophysiology

Deligkaris, Kosmas; Bullmann, Torsten; Frey, Urs

Extracellularly Recorded Somatic and Neuritic Signal Shapes and Classification Algorithms for High-Density Microelectrode Array Electrophysiology Journal Article

Frontiers in Neuroscience, 10 , pp. 421, 2016, ISSN: 1662-453X.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, Neuronal Networks

Electrical Identification and Selective Microstimulation of Neuronal Compartments Based on Features of Extracellular Action Potentials

Radivojevic, Milos; Jäckel, David; Altermatt, Michael; Müller, Jan; Viswam, Vijay; Hierlemann, Andreas; Bakkum, Douglas J

Electrical Identification and Selective Microstimulation of Neuronal Compartments Based on Features of Extracellular Action Potentials Journal Article

Scientific Reports, 6 (1), pp. 1-20, 2016, ISSN: 2045-2322.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, Neuronal Networks, Stimulation

Cortical axons, isolated in channels, display activity-dependent signal modulation as a result of targeted stimulation

Lewandowska, Marta K; Radivojevic, Milos; Jäckel, David; Müller, Jan; Hierlemann, Andreas

Cortical axons, isolated in channels, display activity-dependent signal modulation as a result of targeted stimulation Journal Article

Frontiers in Neuroscience, 10 , pp. 83, 2016, ISSN: 1662453X.

Abstract | Links | BibTeX | タグ: MaxOne, Neuronal Networks, u-Tunnels

Structures of Neural Correlation and How They Favor Coding

Franke, Felix; Fiscella, Michele; Sevelev, Maksim; Roska, Botond; Hierlemann, Andreas; Azeredo da Silveira, Rava

Structures of Neural Correlation and How They Favor Coding Journal Article

Neuron, 89 (2), pp. 409-422, 2016, ISSN: 10974199.

Abstract | Links | BibTeX | タグ: Data Analysis, ETH-CMOS-MEA, Neuronal Networks, Retina

2015

High-resolution CMOS MEA platform to study neurons at subcellular, cellular, and network levels

Müller, Jan; Ballini, Marco; Livi, Paolo; Chen, Yihui; Radivojevic, Milos; Shadmani, Amir; Viswam, Vijay; Jones, Ian L; Fiscella, Michele; Diggelmann, Roland; Stettler, Alexander; Frey, Urs; Bakkum, Douglas J; Hierlemann, Andreas

High-resolution CMOS MEA platform to study neurons at subcellular, cellular, and network levels Journal Article

Lab Chip, 15 (13), pp. 2767-2780, 2015, ISSN: 1473-0197.

Abstract | Links | BibTeX | タグ: MaxOne, Neuronal Networks

Chronic Co-Variation of Neural Network Configuration and Activity in Mature Dissociated Cultures

Okawa, Satoru; Mita, Takeshi; Bakkum, Douglas J; Frey, Urs; Hierlemann, Andreas; Kanzaki, Ryohei; Takahashi, Hirokazu

Chronic Co-Variation of Neural Network Configuration and Activity in Mature Dissociated Cultures Journal Article

Electronics and Communications in Japan, 98 (5), pp. 34-42, 2015, ISSN: 1942-9541.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, Neuronal Networks

Recording large extracellular spikes in microchannels along many axonal sites from individual neurons

Lewandowska, Marta K; Bakkum, Douglas J; Rompani, Santiago B; Hierlemann, Andreas

Recording large extracellular spikes in microchannels along many axonal sites from individual neurons Journal Article

PLoS ONE, 10 (3), pp. 1-24, 2015, ISSN: 19326203.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, Neuronal Networks

2013

Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites

Bakkum, Douglas J; Frey, Urs; Radivojevic, Milos; Russell, Thomas L; Müller, Jan; Fiscella, Michele; Takahashi, Hirokazu; Hierlemann, Andreas

Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites Journal Article

Nature Communications, 4 , pp. 1-12, 2013, ISSN: 2041-1723.

Abstract | Links | BibTeX | タグ: Data Analysis, ETH-CMOS-MEA, Neuronal Networks

Sub-millisecond closed-loop feedback stimulation between arbitrary sets of individual neurons.

Müller, Jan; Bakkum, Douglas J; Hierlemann, Andreas

Sub-millisecond closed-loop feedback stimulation between arbitrary sets of individual neurons. Journal Article

Frontiers in Neural Circuits, 6 , pp. 121, 2013, ISSN: 1662-5110.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, MEA Technology, Neuronal Networks, Stimulation

2012

High-density microelectrode array recordings and real-time spike sorting for closed-loop experiments: an emerging technology to study neural plasticity

Franke, Felix; Jackel, David; Dragas, Jelena; Muller, Jan; Radivojevic, Milos; Bakkum, Douglas J; Hierlemann, Andreas

High-density microelectrode array recordings and real-time spike sorting for closed-loop experiments: an emerging technology to study neural plasticity Journal Article

Frontiers in Neural Circuits, 6 , pp. 105, 2012, ISSN: 1662-5110.

Abstract | Links | BibTeX | タグ: Neuronal Networks, Review, Spike Sorting

2007

A CMOS-based microelectrode array for interaction with neuronal cultures

Hafizovic, Sadik; Heer, Flavio; Ugniwenko, T; Frey, Urs; Blau, Axel; Ziegler, Christiane; Hierlemann, Andreas

A CMOS-based microelectrode array for interaction with neuronal cultures Journal Article

Journal of Neuroscience Methods, 164 (1), pp. 93-106, 2007, ISSN: 0165-0270.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, Neuronal Networks

2006

Single-chip microelectronic system to interface with living cells

Heer, Flavio; Hafizovic, Sadik; Ugniwenko, T; Frey, Urs; Franks, Wendy; Perriard, Evelyne; Perriard, Jean Claude; Blau, Axel; Ziegler, Christiane; Hierlemann, Andreas

Single-chip microelectronic system to interface with living cells Journal Article

Biosensors & Bioelectronics, 22 (11), pp. 2546-2553, 2006, ISSN: 0956-5663.

Abstract | Links | BibTeX | タグ: Cardiomyocytes, ETH-CMOS-MEA, Neuronal Networks

CMOS microelectrode array for bidirectional interaction with neuronal networks

Heer, Flavio; Hafizovic, Sadik; Franks, Wendy; Blau, Axel; Ziegler, Christiane; Hierlemann, Andreas

CMOS microelectrode array for bidirectional interaction with neuronal networks Journal Article

IEEE Journal of Solid-State Circuits, 41 (7), pp. 1620-1629, 2006, ISSN: 00189200.

Abstract | Links | BibTeX | タグ: ETH-CMOS-MEA, MEA Technology, Neuronal Networks, Stimulation