Every Cell Counts.
MxW Bulletin | Edition No. 2 | 2021

Editor's Note

Hello Everyone! 

How are you all doing? I have a confession to make... every year I am always looking forward to participating in the ISSCR Annual Meeting. My first ISSCR Meeting was back in 2017 and I was amazed by the groundbreaking research in stem cell science and regenerative medicine. And so, this week, we at MaxWell Biosystems are celebrating the Stem Cell Week, with several events that we are organizing within the conference and on our own. Why are we so excited about iPSC and organoid research? Find out in this newsletter. 

Here are the contents: Enjoy and please join us in any of our events this week. See you soon!

Special Invitation

Stem Cell Week 2021

The ISSCR Annual Meeting is starting today! MaxWell Biosystems will once again be participating in this conference and we decided to organize the Stem Cell Week 2021, a series of events including an engaging innovation showcase with invited speakers, an exclusive online Live Demo Session of our system, two scientific poster presentations, a virtual booth, and we will also be sponsoring the "Modeling Development" concurrent session.

Even if you are not planning to attend ISSCR 2021, you will be able to access most of our sessions. See the complete program here



Innovation Showcase

Every Cell’s Story: Characterizing the activity of human iPSC derived-neurons in 2D and 3D cultures at high resolution
ISSCR Session with Live Q&A - June 23, Wednesday 
12:00 – 13:00 (EDT) | 18:00 – 19:00 (CEST) | 9:00 – 10:00 (PDT) | 01:00 – 02:00 (JST)
Zoom Webinar Session with Live Q&A - June 24, Thursday
03:00 – 04:00 (EDT) | 09:00 – 10:00 (CEST) | 00:00 – 01:00 (PDT) | 16:00 – 17:00 (JST)

Presentations and Speakers:

  • Intro to MaxWell Biosystems and Welcome Message
    Dr. Urs FreyCEO, MaxWell Biosystems, Switzerland
  • Phenotyping of neurodevelopmental and psychiatric disorders with human iPSC-derived dopaminergic neurons
    Dr. Maria Sundberg, Research Fellow, Boston Children’s Hospital, Harvard Medical School, USA
  • Microphysiological and micropathophysiological systems to address developmental neurotoxicity and neurological disorders
    Dr. Thomas HartungDoerenkamp-Zbinden Chair, Johns Hopkins University, USA
    Dr. Lena SmirnovaResearch Associate, Johns Hopkins University, USA
  • Application of MaxTwo platform in BrainSpheres model
    Dr. David PamiesResearch Fellow, University of Lausanne, Switzerland

You can access the ISSCR Session within the conference platform, or register today to join our Zoom Webinar Session with live Q&A.

Register today!

Live Demo Session

Presenting MaxTwo: A powerful system to characterize the function of human iPSC-derived neurons
Live Session with Q&A - June 24, Wednesday
12:00 -13:00 (EDT) I 18:00 -19:00 (CEST) I 09:00 -10:00 (PDT) I 01:00 -02:00 (JST) 
Presented by Giulio Zorzi, Product Manager & Application Engineer, MaxWell Biosystems

Sign-up to get one of the limited slots to participate in our MaxTwo Live Demonstration. We will be broadcasting from our laboratory here in Switzerland, and you can see how to use the system, learn how our system can help you advance your research, and discuss with us directly if you have any questions.

Sign up for free

Scientific Posters

Label-free functional characterization of human brain organoids at single-cell resolution 
Live Session with Q&A - June 23, Wednesday
00:00 - 01:00 (EDT) | 06:00 -07:00 (CEST) | 21:00 -22:00 (PDT) | 13:00 -14:00 (JST)
Presented by Dr. Szilárd Sajgó, R&D Scientist, MaxWell Biosystems

High-content, label-free functional imaging of human iPSC-derived neuronal cell lines by means of high-density microelectrode arrays 
Live Session with Q&A - June 24, Thursday
00:00 - 01:00 (EDT) | 06:00 -07:00 (CEST) | 21:00 -22:00 (PDT) | 13:00 -14:00 (JST)
Presented by Dr. Michele Fiscella, VP Scientific Affairs, MaxWell Biosystems

You can also find a short presentation of the poster and book a call with the presenters on our website


16p11.2 Deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro

Dr. Maria Sundberg, first author of the Nature Communications article
Dr. Maria Sundberg et al. recently published a very interesting article in Nature Communications about the phenotyping of neurodevelopmental and psychiatric disorders with human iPSC-derived dopaminergic neurons. We would like to congratulate all researchers involved for the very nice work!

We had a wonderful chance to interview Dr. Sundberg about this publication. Get more insights about this work its implication for the development of new therapies for neurodevelopmental and neuropsychiatric disorders associated with 16p11.2 deletion by reading our related blog post!
Check the Article
We are very happy to have Maria as a speaker of our Innovation Showcase during the Stem Cell Week!
Moreover, we are thrilled to have her, together with Hannah Pinson, co-author of the paper, to be the speakers of our upcoming webinar. Make sure to register today!
Register to the Webinar

MxW News

We are Growing! 
The MaxWell Team keeps growing! We are now 30 MaxWellers, dedicating all our efforts to bring the best tools for functional characterization of iPSC-derived neurons into the hands of our customers.

Welcome Aboard!
We are delighted to welcome Dr. Diana Freire to the MxW team! 

Diana joined the team as a Scientific Marketing Specialist and is in charge of creating engaging scientific content. We are excited for what's ahead in the marketing team together with you, Diana!
In-Vitro 2D & 3D Neuronal Networks Summit
We organized the first In-Vitro 2D & 3D Neuronal Networks Summit end of April with over 700 registrants and we are very thankful to you for making it a success. Read more about it, enjoy some behind-the-scenes pictures, and access the replays on this blog post.

Latest Publications using MxW Technology

iPSC-derived Neurons
M. Sundberg,  H. Pinson, R. S. Smith, K. D. Winden, P. Venugopal, D. J. C. Tai, J. F. Gusella, M. E. Talkowski, C. A. Walsh, M. Tegmark, M. Sahin,
"16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro", Nature Communications. 2021 (DOI: 10.1038/s41467-021-23113-z)

See also our Featuring section.
Brain Slices
M. Kajiwara, R. Nomura, F. Goetze, M. Kawabata, Y. Isomura, T. Akutsu, M. Shimono
"Inhibitory neurons exhibit high controlling ability in the cortical microconnectome", PLOS Computational Biology. 2021 (DOI: 
Did we miss to highlight your work? We are doing our best to monitor all publications where our technology has been used, but we may occasionally not be aware or overlook some works. Please let us know by sending an email to info@mxwbio.com so that we can feature your research in our website and newsletters. Feel free to also let us know if you will present in any upcoming conferences or events so that we can also share it in our social media and other channels. Thank you!