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Beyond Neurodegeneration: Functional Signatures of Parkinson’s Disease with HD-MEAs
Parkinson’s disease involves early dysfunction in neuronal activity and circuit dynamics, not only neuronal loss. This blog shows how HD-MEAs and MaxLab Live assays quantify functional metrics across single cells, networks, and axonal pathways in human-relevant PD models.
Spot the Differences in Developing Brain Circuits: How Organoids Replay Innate ‘Backbone’ Burst Motifs
HD-MEA recordings reveal recurring “backbone” burst motifs in developing brain organoids and neonatal slices. The study highlights structured early network activity not seen in 2D cultures.
Getting Started with Closed-Loop Experiments on HD-MEAs
A practical introduction to building real-time feedback loops with stimulation and recording on HD-MEAs. This post shows the core workflow behind closed-loop experiments in MaxLab Live.
Closed-loop training of organoids to balance a Cartpole (Inverted Pendulum)
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Can living cortical organoids learn a control task? Robbins et al. show they can, balancing a cartpole via real-time, closed-loop stimulation on MaxOne HD-MEAs.
Mapping Neuronal Diversity: Functional Validation of Induced Neurons with HD-MEAs and DeePhys
Dive into a Science validating induced-neuron diversity by linking transcriptomics to electrophysiology with MaxTwo + DeePhys.
New Therapeutic Target in the Fight Against ALS
A Nature study presents a human iPSC-derived neuronal network model that reveals how TDP-43 dysfunction drives neurotoxicity in ALS/FTLD and highlights NPTX2 as a promising therapeutic target. Using MaxWell Biosystems' MaxOne HD-MEAs, the team captured high-resolution functional readouts of these networks, supporting detailed characterization from network down to single-cell features.
MaxWell Biosystems Launches Commercial Expansion: Strengthening Regional Presence in EMEA
MaxWell Biosystems AG is advancing its global go-to-market strategy with the establishment of a dedicated EMEA regional team, expanding its presence and partnerships across Europe, the Middle East, and Africa.