Discover how the human retina actively synchronizes visual signals to create seamless perception, with new insights into the precise timing of foveal visual pathways. Leveraging MxW Bio’s HD-MEA technology and a multidisciplinary approach, the work reveals neural computation mechanisms at subcellular resolution.

This webinar presents how combining transcription factor overexpression with developmental signaling modulation enables the generation of diverse human neuron types. It highlights large-scale single-cell transcriptomics and functional profiling approaches used to link neuronal identity with activity, connectivity, and maturation.

Learn how combining MaxTwo Multi-Well High-Density MEA technology with FUJIFILM hiPSC-derived neurons enables advanced investigation of neurodegenerative disease mechanisms, including comparative analyses of Parkinson’s, ALS, and FTD models versus healthy controls. The talk also highlights how optimized HD-MEA assays detect subtle functional phenotypes to precisely characterize disease models.

Learn how micro- and nano-channel PDMS platforms enable directional neuronal network fabrication at single-neuron resolution and support personalized disease modeling using patient-derived cells. The talk also demonstrates how biophysical modeling and information-theoretic analysis of neuronal networks on a chip reveal synaptic receptor alterations and altered information flow in glioblastoma-infiltrated networks.

Learn how inter-regional connectivity underlies complex brain functions and how neural organoid networks can model these circuits in vitro. The talk highlights how HD-MEAs enable detailed analysis of organoid network activity and functional connectivity.