Microphysiological Systems

The flat planar surface of MaxWell Biosystems’ HD-MEAs supports easy integration of compartmentalized systems and chip-based platforms, whether PDMS-based or other materials. With this MPS-compatible surface, structures remain well attached on the HD-MEA surface for longitudinal experiments.

With dense, full-area electrode coverage, functional regions of MPS structures including axonal tunnels are reliably captured without the need for micrometer-level alignment. Researchers can simply place the MPS structures, culture the cells, and begin recording. This streamlined setup reduces preparation time and enables efficient scaling of MPS-based experiments.

Easily identify which electrodes are exposed to cells within the MPS structures, enabling targeted stimulation and recording from specific compartments.

Capture spontaneous and evoked activity with subcellular resolution, including axonal propagation and low-amplitude signals across channels, bridges, and microtunnels. This high sensitivity supports consistent, reproducible results across experiments.

Deliver localized electrical stimulation using individually addressable electrodes, ideal for probing connectivity, synaptic strength, and circuit responses within defined regions of the MPS.