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MaxLab Live
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MaxLab Live is the all-in-one software for recording, analyzing, and interacting with biological samples using MaxOne and MaxTwo systems. Whether scaling up with powerful built-in tools or customizing experiments beyond standard applications, MaxLab Live simplifies complex protocols with an intuitive and versatile interface built to support both standard and exploratory applications.
All your tools in one interface
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Visualize
Explore cell activity in real time and high-resolution
Increase throughput without compromising data quality. Each well features 26,400 electrodes at a density of 3,265 electrodes/mm², maintaining single-cell and subcellular resolution across the entire plate.
Record
Easily capture electrophysiological data
Recording biologically relevant data is essential to fully understand your model. Easily capture high-quality, high-content datasets through an intuitive and streamlined workflow.
Stimulate
Interact with your cells through electrical stimulation
Interacting with electrogenic cells is key to understanding how networks process and adapt to inputs. Apply targeted, customizable electrical stimulation protocols, and observe population responses as they happen.
Analyze
Extract standard and novel readouts across scales with ease
Turning rich electrophysiological data into actionable insights requires easy, reliable access to the most relevant readouts. Extract key physiological characteristics using automated analysis tools that transform complex data into ready-to-use, publication-quality results.
High-content electrophysiology made simple
Transform complex electrophysiology into an intuitive experience. MaxLab Live simplifies and streamlines experimental workflows with optimized, ready-to-use Assays tailored for specific applications. Combine assays into streamlined experimental pipelines to achieve the most effective recording strategies and uncover meaningful and novel data from your biological sample.
Assay framework for standardized experiments
MaxLab Live Assays are predefined, reusable experiment templates that guide users through a structured workflow: configure recording strategy, run experiments with consistent settings, and inspect the results through intuitive visualizations. This repeatable framework supports scientific rigor while saving time on setup and analysis.
Modular design
Assays can run independently or be combined within the same session, allowing workflow customization while maintaining consistency. Once configured, experiments can run in the background, freeing up time for other tasks.
Tailored for your scientific questions
Each Assay is purpose-built with specific experimental objectives in mind. Optimized data acquisition and analysis strategies ensure that relevant high-quality data are captured, processed, summarized, and exported with minimal effort.
Inside MaxLab Live Assays
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ActivityScan
Are your cells active?
Where are they located?
Functional & spatial Insights
Precisely identify where your cells are located and characterize their activity patterns.
Your sample summarized
Thoroughly check the activity of your sample to assess health, coverage, and readiness for further experiments.
Heatmap of firing rate, illustrating overall neural activity across the chip.
Heatmap of spike amplitude, showing overall signal strength across the chip.
Network
Are your cells interconnected?
Identify network-level synchronized activity
With optimized recording strategies, effortlessly assess and quantify synchronous activity patterns across many neurons interconnected with one another within the population network.
Development and maturation monitoring
Track evolving network dynamics over time to monitor the maturation of your samples.
Raster plot of neural activity. Each blue dot marks a spike on a given recording electrode. This reveals overall firing dynamics across recorded neurons.
Smoothed firing rate trace showing how overall activity changed over time. Peaks marked with black dots highlight network bursts.
Stimulation
How do your cells respond to electrical stimulation?
Precise electrical stimulation
Precisely identify where your cells are located and characterize their activity patterns.
Evoked activity characterization
Go beyond spontaneous activity and characterize the electrically evoked activity patterns of your samples.
Peristimulus time histogram showing how neurons responded to electrical stimulation across multiple trials. Color indicates the number of spikes evoked, highlighting increased activity after stimulation.
Box plots illustrating how evoked response strength varies with stimulation amplitude. Stronger stimulation elicits stronger neural activity.
AxonTracking
How do signals travel through the axons of your neurons?
Label-free axonal reconstruction
Visualize axonal branches without the need for dyes or additional sample preparation by tracking the action potential propagation of your cells.
Conduction velocity measurement
Investigate the speed at which action potentials propagate through your cells.
Multiple neurons recorded with the Axon Tracking Assay. Contour maps show their detected signals, with red lines indicating action potential propagation along axonal arbors.
Axonal action potentials from single neurons propagating across the MEA, recorded at high resolution.
Scale up or customize: MaxLab Live adapts to every workflow
Whether running hundreds of experiments or developing advanced, non-standard experimental protocols beyond Assays, MaxLab Live provides the flexibility and control to meet a wide range of scientific needs. Built-in tools enable both high-throughput analysis and deep customization through direct data access and programmable workflows.
Scale – Built for throughput
Easy experiment management
Parallel analysis and data export
Fast annotation and reporting
Explore High-Throughput Features
Customize – Built for control
Access live data stream
Dynamic control
Develop workflows
Explore the API
Data handling designed
for high-throughput
Simplify the complexity of scaling up experiments with MaxLab Live’s high-throughput data management and analysis features. Organize, analyze, and share results from hundreds of experiments in parallel, efficiently and reliably.
Manage your digital lab notebook
Handle large-scale experiments with ease using the Annotations Tab. Tag, filter, and structure data across time points, treatment conditions, or custom groupings. All recordings remain connected, searchable, and structured for downstream analysis in MaxLab Live and custom pipelines.
Analyze experiments in parallel
Apply a consistent analysis pipeline across multiple datasets and run all analyses simultaneously in MaxLab Live. Run batch analyses, export summary metrics, perform quality checks, or explore individual wells, all within a few clicks.
Generate summary reports
Automatically generate structured reports for your entire experiment, including plots, tables, and annotations.
Share results with ease
Built to streamline high-throughput workflows, the MaxLab Live large-scale data handling suite simplifies the organization, analysis, and sharing of HD-MEA data. Whether generating reports, sharing findings, or preparing publication-ready figures, MaxLab Live tools ensure that the results are accessible and presentation-ready in just a few clicks, and available in multiple formats for seamless collaboration and communication.
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API for deeper control and
advanced electrophysiology
The MaxLab Live API opens the door to programmable, integrated, and adaptive experimentation with MaxWell Biosystems' high-density microelectrode array (HD-MEA) systems. From building real-time closed-loop systems to deploying custom stimulation protocols, the API delivers unmatched flexibility and control over electrophysiological experiments.
API Core
Features
Real-time data access and control
Access raw data streams in real time to detect spikes, bursts, or user-defined events as they occur. Enable responsive experimentation with live feedback.
Customized stimulation
Design and execute programmable stimulation protocols tailored to specific research questions. Control electrode selection, waveform parameters, and timing with precision.
Advanced system integration
Enable advanced integration between MaxLab Live and external hardware or software platforms. The API supports real-time communication and synchronized multimodal workflows, including coordination with lab automation systems for seamless, plug-and-play operation.
Programmable experiment logic
Develop custom logic for signal processing, adaptive stimulation, or feedback loops, and more. Whether implementing real-time event detection or complex looped conditions, MaxLab Live API enables advanced experimental needs.
MaxLab Live
API Documentation
This documentation is designed to help users understand and implement the API effectively, making it easy to get started and build advanced workflows with confidence.
Access the documentation
Resources
Product Documentation
MaxLab Live Manual
This manual provides a complete guide to using MaxLab Live software, from setup and data acquisition to analysis and multiplate workflows.
Product Documentation
MaxLab Live API Module Overview
Unlock MaxLab Live’s API module: real-time data access, custom workflows, external integrations, and advanced stimulation control for enhanced experimental capabilities.
H. Cai et al.
Brain organoid reservoir computing for artificial intelligence
Nature Electronics
|
2023
D. McSweeney, R. Gabriel, K. Jin, Z. P. Pang, B. Aronow, and C. Pak
CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
iScience
|
2022
M. Sundberg et al.
16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro
Nature Communications
|
2021
Nina Dirkx
Weckhuysen Lab, VIB – University of Antwerp Center for Molecular Biology, Belgium
“The Batch Analysis and Report Generation modules are heaven on earth. They make handling massive datasets feasible and cut our workload by 20-fold or more. Feeding results directly into reports streamlined our work, even for small projects, and the auto-generated PDF really boosted our QC. It truly saved us!”
Dr. Maria Sundberg
Sahin Lab, Neurology Department Boston Children’s Hospital/Harvard Medical School, USA
“With MaxLab Live Software we analyze the neuronal network firing rate and network bursting phenotypes. We also use the AxonTracking Assay to analyze the neuronal branches and their functionality at the single cell level.”
Dr. Rouhollah Habibey
Busskamp Lab, University of Bonn, Germany
“We use the Activity Scan and Network Assay to track the dynamic changes in activity maps of growing networks of human iPSC-derived neurons over time. We found that these changes in activity image match well with dynamics of growing network morphology. This is only possible by High-Density MEAs like MaxOne Chip and user-friendly MaxLab Live Software provided by MaxWell Biosystems.”
Dr. Danny McSweeney
Pak Lab, University of Massachusetts Amherst, USA
“The built-in analysis module was the best part of the MaxLab Live Software. I have little to no experience with analyzing this type of dataset and no familiarity with programs like R and MATLAB. The ability to easily analyze data with the MaxLab Live Software was wonderful, with suggested defaults, multiple export runs in single files and further data wrangling and graphing.”
How to
Get Started
Call our Experts
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System Setup
Learn how to set up your system and get ready for your experiments
Product Documentation
Training with Experts
Let our experts guide you through culturing your sample and acquiring high-quality data with confidence
Protocols
Support and Resources
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