Close-up of a robotic arm handling a MaxWell 24-Well Plate inside a laboratory automation machine.

Automated
high-content
electrophysiology

Hands-off precision, at scale.

MaxWell Biosystems provides High-Density Microelectrode Array (HD-MEA) platforms that capture high-resolution functional electrophysiology readouts from electrogenic biological models.

We designed MaxTwo around what our users need most: precision, reliability, and the ability to scale. Its compact footprint enables straightforward integration into a wide range of lab facilities, from standalone setups to automated workflows.

As drug discovery and translational research increasingly rely on automation to expand throughput and standardize workflows, MaxTwo is built to fit into automated lab environments, helping teams reduce variability and deliver reproducible functional readouts.
With API access and software designed for large-scale data handling, including batch processing, structured annotations, and streamlined exports, teams can run standardized studies and generate data they can trust.

We work with teams interested in integration to define and implement workflows tailored to their automation setup.

MaxTwo,
Automated

MaxTwo Product Page

Key features

High-throughput functional electrophysiology readouts from 2D and 3D electrogenic models, powered by next-gen HD-MEA technology.

High-density coverage for reproducible sampling

Dense sensing in every well ensures representative sampling across the culture, increasing statistical power and supporting consistent results.

High-resolution readouts across scales

Measure functional activity across network, cellular, and sub-cellular levels to support high-content phenotyping within each well.

High sensitivity and precise stimulation in every well

Low-noise recordings capture subtle signals, while flexible stimulation enables controlled probing of responses, timing, and connectivity.

Scale-up and Automation

Designed for scale, MaxTwo combines high-throughput plate formats with automation-compatible integration and software built for standardized execution.

Parallel multi-well throughput

Available with 6- and 24-Well Plates, compatible with the upcoming 96-Well Plate.

Automation-ready integration and API for hands-off workflows

Designed to fit into automated lab environments, with API access for programmable workflows and advanced integration into automated pipelines.

High-throughput analysis and reporting in MaxLab Live

Scale to large study sets with structured annotations and streamlined exports, supported by the MaxLab Live Batch Analysis Module and Report Generation Module for standardized processing and reporting.

MaxTwo device with a blue sliding cover revealing a black tray holding a 24-Well Plate.

Duncan NRI: Scaling human brain cell models with fully automated functional readouts

At the Jan and Dan Duncan Neurological Research Institute, teams are scaling human brain cell models to accelerate research into neurodegeneration and other brain disorders. In collaboration with Automata, the institute has implemented the LINQ automation platform to expand the speed, scale, and rigor of cell model generation, maintenance, and characterization.

MaxTwo Multi-Well HD-MEA System adds functional electrophysiology readouts within this fully automated workflow. Watch the video below for more information, and explore the Duncan NRI announcement and coverage for additional context.

Related press releases:

Leading US research center, Duncan Neurological Research Institute, partners with Automata to automate studies of human brain cell models

Duncan NRI partners with Automata to automate studies of human brain cell models

Related
Applications 

Neuronal Cell Cultures
Organoids
Disease Modeling
Pharmacology & Toxicology
Functional Phenotyping

Dr. Mirjana Maletić-Savatić

Baylor College Medicine, US

Integrating LINQ with MaxTwo gives us full automation with high quality electrophysiology. We can run larger studies at pace while keeping consistent and reproducible readouts which strengthens our conclusions.

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Get in touch

Interested in adding functional electrophysiology readouts to your automated facility?

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