Method development with MaxWell Biosystems’ high-density microelectrode arrays (HD-MEAs) involves designing and refining experimental setups, protocols, and analysis pipelines to optimize HD-MEA use for specific biological models and research goals. Our platforms support advanced method development through flexible electrode configurations, high-resolution signal acquisition, and intuitive, powerful software featuring Application Programming Interface (API) access and open data formats. Researchers can precisely tailor recording strategies, design custom stimulation protocols, and develop advanced analysis tools to extract novel functional metrics from rich, high-density recordings.
Importantly, method development also includes integrating HD-MEA recordings with complementary techniques such as microscopy, optogenetics, calcium imaging, and patch clamp electrophysiology. These multimodal approaches provide a more comprehensive view of neuronal structure and function, enabling cross-validation and deeper mechanistic insight. The compact form factor of the MaxOne recording units facilitates seamless combination with microscopy, environmental control systems, and custom lab setups. Low light sensitivity further supports integration with optogenetic tools and live-cell imaging.
Whether refining protocols for brain organoids, optimizing stimulation strategies, advancing large-scale data analysis, or developing multimodal workflows, MaxWell Biosystems’ flexible, automation-compatible HD-MEA platforms empower tailored method development that drives innovation across neuroscience, disease modeling, and drug discovery.
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