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iScience
|
2026
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Unperturbed Dye-based Imaging of Spontaneous Synchronized Calcium Activity in iPSC-derived Neuronal Cultures

Nina Dirkx, Bob Asselbergh, Peter Verstraelen, Jonas Van Lent, Els De Vriendt, Vincent Timmerman, Winnok H. De Vos, Sarah Weckhuysen
Journal Article
Functional Phenotyping
Neuronal Cell Cultures
MaxLab Live
MaxTwo
Molecular Psychiatry
|
2026
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Loss of schizophrenia risk gene XPO7 disrupts neuronal excitability and network regularity via altered Na+ channel dynamics in human neurons

Lei Cui, Erkin Kurganov, Derek Hawes, Philipp Hornauer, Raozhou Lin, Yining Wang, Andreas Hierlemann, Morgan Sheng, Ralda Nehme, Jen Q. Pan
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxTwo
algorithms
|
2026
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In Vitro to In Vivo: Bidirectional and High-Precision Generation of In Vitro and In Vivo Neuronal Spike Data

Masanori Shimono
Journal Article
Method Development
MaxLab Live
MaxOne
iScience
|
2026
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An integrated in vitro platform and biophysical modeling approach for studying synaptic transmission in isolated neuronal pairs

Giulia Amos, Vaiva Vasiliauskaitė, Jens Duru, Maria Leonor Azevedo Saramago, Tim Schmid, Alexandre Suter, Ferran Cid Torren, Joël Küchler, Tobias Ruff, János Vörös, Katarina Vulić
Journal Article
Microphysiological Systems
Neuronal Cell Cultures
MaxLab Live
MaxOne
Cell Reports Methods
|
2026
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Wnt activation and dual SMAD inhibition for induction and maintenance of hindbrain-like neural stem cell from hiPSCs

Ziadoon Al-Akashi, Denise Zujur, Nicholas Boyd-Gibbins, Nathalie Eileen Wiguna, Masato Nakagawa, Tetsuhiro Kikuchi, Asuka Morizane, Jun Takahashi, Makoto Ikeya
Journal Article
Functional Phenotyping
MaxLab Live
MaxOne
STAR Protocols
|
2026
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Protocol for tailored in vitro neuronal networks on high-density microelectrode arrays with polydimethylsiloxane microstructures

Anna-Christina Haeb, Hideaki Yamamoto, Paul Roach, Daniel Merryweather, Yuya Sato, Daniel Tornero, Jordi Soriano
Journal Article
Method Development
Microphysiological Systems
Neuronal Cell Cultures
MaxLab Live
MaxOne
Journal of Neuroscience Methods
|
2026
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A fast and simple algorithm for accurate spike detection in HD-MEA recordings

Juan Zegers-Delgado, Nathaniel Renegar, Kasun Pathirage, Timothy K Horiuchi, Pamela Abshire, Ricardo C. Araneda
Journal Article
Method Development
MaxLab Live
MaxOne
Proceedings of the National Academy of Sciences
|
2026
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Online supervised learning of temporal patterns in biological neural networks under feedback control

Yuki Sono, Hideaki Yamamoto, Yusei Nishi, Takuma Sumi, Yuya Sato, Ayumi Hirano-Iwata, Yuichi Katori, Shigeo Sato
Journal Article
Biocomputing
Neuronal Cell Cultures
MaxLab Live
MaxOne
Stem Cell Reports
|
2026
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Establishing mouse forebrain organoids as models of intrinsic cortical network assembly

Sebastian Hernandez, Hunter E. Schweiger, Isabel Cline, Gregory A. Kaurala, Ash Robbins, Daniel Solis, Samira Vera-Choqqueccota, Jinghui Geng, Tjitse Van Der Molen, Francisco Reyes, Chinweike Norman Asogwa, Kateryna Voitiuk, Mattia Chini, Marco Rolandi, Sofie R. Salama, Bradley M. Colquitt, Tal Sharf, David Haussler, Mircea Teodorescu, Mohammed A. Mostajo-Radji
Journal Article
Functional Phenotyping
MaxLab Live
MaxOne
iScience
|
2026
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Modeling embryonic heart vascular plexus development and sympathetic innervation on a human heart organoid

Mariana A. Branco, Jacek Marzec, Mafalda Marques Nunes, Marta Bica, Ana Luísa Rayagra, Miguel F. Tenreiro, Joaquim M.S. Cabral, Maria Margarida Diogo
Journal Article
Functional Phenotyping
Organoids
MaxLab Live
MaxOne
Brain Research
|
2026
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Elevated FKBP5 expression associates with epilepsy-related molecular changes and promotes neuronal hyperexcitability

Meng Cai, Shuyang Wang, Mingsu Liu, Bin Lai, Chen Chen, Jing Ding, Xin Wang
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
medRxiv
|
2026
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O-GlcNAcase dosage variants are associated with neuronal deficits and intellectual disability

Florence Authier, Benedetta Attianese, Oscar G. Sevillano-Quispe, Kevin-Sebastien Coquelin, Sergio Galan Bartual, Huijie Yuan, Manuel Peral Vazquez, Iria Esperon-Abril, Andrew T. Ferenbach, Carsten Scavenius, Diane Doummar, Perrine Charles, Cyril Mignot, Magdalena Krygier, Boris Keren, Maria Mazurkiewicz-Beldzinska, Palle Duun Duun Rohde, Per Qvist, Daan van Aalten
Preprint
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxTwo
Advanced Science
|
2026
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Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

Elisa M Cruz, Luana C Soares, Gretchen Greene, Fernando Messore, Mohammed Abuelem, Mingyu Li, Caroline Andersen, Mirriam Domocos, Elisa Vitiello, Rabeah Abdul Razak, Marlene Lawston, Gabriel Moser, Talia Vasaturo-Kolodner, Mona Barkat, Roslyn M Bill, Edward Mann, Linna Zhou, Mootaz M Salman, Hagan Bayley, Zoltán Molnár, Francis G Szele
Journal Article
Disease Modeling
Functional Phenotyping
Brain Slices
MaxOne
Cell Reports
|
2026
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Goal-directed learning in cortical organoids

Ash Robbins, Hunter E. Schweiger, Sebastian Hernandez, Alex Spaeth, Kateryna Voitiuk, David F. Parks, Tjitse van der Molen, Jinghui Geng, Isabel Cline, Kenneth S. Kosik, Sofie R. Salama, Tal Sharf, Mohammed A. Mostajo-Radji, David Haussler, Mircea Teodorescu
Journal Article
Biocomputing
Organoids
MaxLab Live
MaxOne
Stem Cell Reviews and Reports
|
2026
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Human Myelin Spheres for in Vitro Oligodendrocyte Maturation, Myelination and Neurological Disease Modeling

Karan Ahuja, Roya Ramezankhani, Xinyu Wang, Thibaut Burg, Giulia Amos, Katrien Neyrinck, Alessio Silva, Geethika Arekatla, Eleanor Eva Cassidy, Fatemeharefeh Nami, Joke Terryn, Keimpe Wierda, Katlijn Vints, Niels Vandamme, Suresh Poovathingal, Ivo Lambrichts, Johannes V. Swinnen, Ludo Van Den Bosch, Lies De Groef, Lieve Moons, Catherine Verfaillie, Johan Neyts, Dirk Jochmans, Yoke Chin Chai
Journal Article
Functional Phenotyping
Organoids
MaxLab Live
MaxTwo
bioRxiv
|
2026
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Capturing self-renewing multipotent neural crest stem cells from human pluripotent stem cells

Yayoi Toyooka, Nami Kawaraichi, Daisuke Kamiya, Teruyoshi Yamashita, Yusaku Komoike, Kimiko Fukuda, Teppei Akaboshi, Hirokazu Matsumoto, Makoto Ikeya
Preprint
Functional Phenotyping
MaxLab Live
MaxTwo
bioRxiv
|
2026
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A three-compartment microfluidic platform for investigating signal transmission in the human sensory pathway†

Blandine F. Clément, Trui Osselaer, Claire Zhang, Giacomo Paccagnan, Tobias Ruff, János Vörös
Preprint
Method Development
Microphysiological Systems
Organoids
MaxOne
NanoImpact
|
2026
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Polystyrene nanoplastics modulate neurite length in a size-specific manner

Veronika Górová, Thuy Thi Lai, Alexey M. Afonin, Kore Nemeth, Anssi Pelkonen, Tarja Malm, Pasi Jalava, Riikka Lampinen, Katja M. Kanninnen
Journal Article
Pharmacology & Toxicology
Neuronal Cell Cultures
MaxLab Live
MaxOne
Lab on a Chip
|
2026
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MyeliMAP: a microfluidic-multielectrode array hybrid platform to investigate oligodendrocyte function in human iPSC derived brain-like networks

Karan Ahuja, Blandine F. Clément, Giulia Amos, Joël Küchler, Keimpe Wierda, Yoke Chin Chai, Lieve Moons, Catherine Verfaillie
Journal Article
Microphysiological Systems
Neuronal Cell Cultures
MaxOne
Cells
|
2026
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Network Hypoactivity in ALG13-CDG: Disrupted Developmental Pathways and E/I Imbalance as Early Drivers of Neurological Features in CDG

Rameen Shah, Rohit Budhhraja, Silvia Radenkovic, Graeme Preston, Alexia Tyler King, Sahar Sabry, Charlotte Bleukx, Ibrahim Shammas, Lyndsay Young, Jisha Chandran, Seul Kee Byeon, Ronald Hrstka, Doughlas Y. Smith, Nathan P. Staff, Richard Drake, Steven A. Sloan, Akhilesh Pandey, Eva Morava, Tamas Kozicz
Journal Article
Disease Modeling
MaxLab Live
MaxTwo
Nature Neuroscience
|
2026
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Axonal Eif5a hypusination controls local translation and mitigates defects in FUS-ALS

Diana Piol, Bilal Khalil, Tessa Robberechts, Theo Killian, Maria Georgopoulou, Gabriele Partel, David Wouters, Nikolai Hecker, Paraskevi Tziortzouda, Yana Verresen, Nikky Corthout, Sam Kint, Katy Vandereyken, Philip Van Damme, Thierry Voet, Kristofer Davie, Suresh Poovathingal, Ludo Van Den Bosch, Stein Aerts, Alejandro Sifrim, Sandrine Da Cruz
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxTwo
STAR Protocols
|
2025
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Protocol for the enhanced analysis of electrophysiological data from high-density multi-electrode arrays with nicespike and spikeNburst

Robert Wolff, Alessia Polito, Alessio Paolo Buccino, Michela Chiappalone, Valter Tucci
Journal Article
Method Development
Neuronal Cell Cultures
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Journal of Neurophysiology
|
2025
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Microscale maps of bursting dynamics across human hippocampal slices from epilepsy patients

Matthew A.T. Elliott, John P. Andrews, Tjitse van der Molen, Jinghui Geng, Alex Spaeth, Anna Toledo, Kateryna Voitiuk, Cordero Core, Thomas Gillespie, Ari Sinervo, David F. Parks, Ash Robbins, Daniel Solís, Edward F. Chang, Tomasz Jan Nowakowski, Mircea Teodorescu, David Haussler, Tal Sharf
Journal Article
Disease Modeling
Functional Phenotyping
Brain Slices
MaxLab Live
MaxOne
Journal of Advanced Research
|
2025
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Butylphthalide enhances neurorestoration following ischemic stroke by restructuring microvasculature through vimentin modulation

Haiyan Xiao, Haochen Xie, Meng Qin, Chenwei Zuo, Ruimao Zheng, Shaochan Zhang, Shiyi Sun, Jingxue Ye, Min Wang, Yu Tian, Li Cao, Guibo Sun
Journal Article
Disease Modeling
Pharmacology & Toxicology
Neuronal Cell Cultures
MaxLab Live
MaxOne
Microsystems & Nanoengineering
|
2025
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Microelectrode arrays cultured with in vitro neural networks for motion control tasks: encoding and decoding progress and advances

Sihan Hua, Yaoyao Liu, Jinping Luo, Shangchen Li, Longhui Jiang, Pei Wu, Shutong Sun, Li Shang, Chengji Lu, Kui Zhang, Juntao Liu, Mixia Wang, Huaizhang Shi, Xinxia Cai
Journal Article
Biocomputing
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