Blog & News
Science, stories, and insights from the people driving research forward.
Microphysiological Systems: From Structure to Computation in the Brain
From organoids to engineered microstructures, MPS let researchers build structure into neural circuits rather than just observe it, opening a path to studying brain computation.
Why Flexibility Matters in HD-MEA Recordings
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Biology does not grow in a grid. Switch Matrix technology helps researchers find relevant activity and flexibly select low-noise recording and stimulation sites.
MaxLab Live 26.1: Advanced Analysis for High-Content Electrophysiology
MaxLab Live 26.1 introduces novel neuronal and cardiac analysis capabilities to help researchers extract deeper insights from HD-MEA recordings. New readouts, parameter-free workflows, and tailored exports simplify analysis from acquisition to downstream comparison.
How Can Engineered Neuronal Networks Advance Neurocomputing?
Prof. Hideaki Yamamoto answers audience questions on engineered neuronal networks, reservoir computing, biological versus artificial intelligence, and training living networks.
How Can Human Neural Models Better Support Development and Disease Research?
Experts answer audience questions on human neural models, neurodegenerative disease, spatial transcriptomics, axonal vulnerability, and neuronal function.
Beyond Neurodegeneration: Functional Signatures of Parkinson’s Disease with HD-MEAs
Parkinson’s disease involves early dysfunction in neuronal activity and circuit dynamics, not only neuronal loss. This blog shows how HD-MEAs and MaxLab Live assays quantify functional metrics across single cells, networks, and axonal pathways in human-relevant PD models.
Spot the Differences in Developing Brain Circuits: How Organoids Replay Innate ‘Backbone’ Burst Motifs
HD-MEA recordings reveal recurring “backbone” burst motifs in developing brain organoids and neonatal slices. The study highlights structured early network activity not seen in 2D cultures.
Getting Started with Closed-Loop Experiments on HD-MEAs
A practical introduction to building real-time feedback loops with stimulation and recording on HD-MEAs. This post shows the core workflow behind closed-loop experiments in MaxLab Live.
Closed-loop training of organoids to balance a Cartpole (Inverted Pendulum)
Can living cortical organoids learn a control task? Robbins et al. show they can, balancing a cartpole via real-time, closed-loop stimulation on MaxOne HD-MEAs.
Mapping Neuronal Diversity: Functional Validation of Induced Neurons with HD-MEAs and DeePhys
Dive into a Science validating induced-neuron diversity by linking transcriptomics to electrophysiology with MaxTwo + DeePhys.
MaxWell Biosystems Launches Commercial Expansion: Strengthening Regional Presence in EMEA
MaxWell Biosystems AG is advancing its global go-to-market strategy with the establishment of a dedicated EMEA regional team, expanding its presence and partnerships across Europe, the Middle East, and Africa.
New Therapeutic Target in the Fight Against ALS
A Nature study presents a human iPSC-derived neuronal network model that reveals how TDP-43 dysfunction drives neurotoxicity in ALS/FTLD and highlights NPTX2 as a promising therapeutic target. Using MaxWell Biosystems' MaxOne HD-MEAs, the team captured high-resolution functional readouts of these networks, supporting detailed characterization from network down to single-cell features.
Microphysiological Systems: From Structure to Computation in the Brain
From organoids to engineered microstructures, MPS let researchers build structure into neural circuits rather than just observe it, opening a path to studying brain computation.
Why Flexibility Matters in HD-MEA Recordings
Biology does not grow in a grid. Switch Matrix technology helps researchers find relevant activity and flexibly select low-noise recording and stimulation sites.
How Can Engineered Neuronal Networks Advance Neurocomputing?
Prof. Hideaki Yamamoto answers audience questions on engineered neuronal networks, reservoir computing, biological versus artificial intelligence, and training living networks.
How Can Human Neural Models Better Support Development and Disease Research?
Experts answer audience questions on human neural models, neurodegenerative disease, spatial transcriptomics, axonal vulnerability, and neuronal function.
Beyond Neurodegeneration: Functional Signatures of Parkinson’s Disease with HD-MEAs
Parkinson’s disease involves early dysfunction in neuronal activity and circuit dynamics, not only neuronal loss. This blog shows how HD-MEAs and MaxLab Live assays quantify functional metrics across single cells, networks, and axonal pathways in human-relevant PD models.
Spot the Differences in Developing Brain Circuits: How Organoids Replay Innate ‘Backbone’ Burst Motifs
HD-MEA recordings reveal recurring “backbone” burst motifs in developing brain organoids and neonatal slices. The study highlights structured early network activity not seen in 2D cultures.
Getting Started with Closed-Loop Experiments on HD-MEAs
A practical introduction to building real-time feedback loops with stimulation and recording on HD-MEAs. This post shows the core workflow behind closed-loop experiments in MaxLab Live.
Closed-loop training of organoids to balance a Cartpole (Inverted Pendulum)
Can living cortical organoids learn a control task? Robbins et al. show they can, balancing a cartpole via real-time, closed-loop stimulation on MaxOne HD-MEAs.
Mapping Neuronal Diversity: Functional Validation of Induced Neurons with HD-MEAs and DeePhys
Dive into a Science validating induced-neuron diversity by linking transcriptomics to electrophysiology with MaxTwo + DeePhys.
New Therapeutic Target in the Fight Against ALS
A Nature study presents a human iPSC-derived neuronal network model that reveals how TDP-43 dysfunction drives neurotoxicity in ALS/FTLD and highlights NPTX2 as a promising therapeutic target. Using MaxWell Biosystems' MaxOne HD-MEAs, the team captured high-resolution functional readouts of these networks, supporting detailed characterization from network down to single-cell features.
MaxLab Live 26.1: Advanced Analysis for High-Content Electrophysiology
MaxLab Live 26.1 introduces novel neuronal and cardiac analysis capabilities to help researchers extract deeper insights from HD-MEA recordings. New readouts, parameter-free workflows, and tailored exports simplify analysis from acquisition to downstream comparison.
MaxWell Biosystems Launches Commercial Expansion: Strengthening Regional Presence in EMEA
MaxWell Biosystems AG is advancing its global go-to-market strategy with the establishment of a dedicated EMEA regional team, expanding its presence and partnerships across Europe, the Middle East, and Africa.