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Brain Communications
|
2022
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P97/VCP ATPase inhibitors can rescue p97 mutation-linked motor neuron degeneration

F Wang, S Li, T Y Wang, G A Lopez, I Antoshechkin, T F Chou
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxTwo
MRS Bulletin
|
2022
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Functional imaging of brain organoids using high-density microelectrode arrays

Manuel Schröter, Congwei Wang, Marco Terrigno, Philipp Hornauer, Ziqiang Huang, Ravi Jagasia, Andreas Hierlemann
Journal Article
Pharmacology & Toxicology
Organoids
MaxLab Live
MaxOne
MaxTwo
Frontiers in Molecular Neuroscience
|
2022
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Aging-dependent altered transcriptional programs underlie activity impairments in human C9orf72-mutant motor neurons

Daniel Sommer, Sandeep Rajkumar, Mira Seidel, Amr Aly, Albert Ludolph, Ritchie Ho, Tobias M Boeckers, Alberto Catanese
Journal Article
Disease Modeling
Pharmacology & Toxicology
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2022
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Automated detection of extracellular action potentials from single neurons

Zhuowei Cheng, Elmer Guzman, Tjitse van der Molen, Tal Sharf, Paul K. Hansma, Kenneth S. Kosik, Linda Petzold, Kenneth R. Tovar
Preprint
Neuronal Cell Cultures
MaxLab Live
MaxOne
Small
|
2022
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A Biodegradable Magnetic Microrobot Based on Gelatin Methacrylate for Precise Delivery of Stem Cells with Mass Production Capability

Seungmin Noh, Sungwoong Jeon, Eunhee Kim, Untaek Oh, Danbi Park, Sun Hwa Park, Sung Won Kim, Salvador Pané, Bradley J. Nelson, Jin-young Kim, Hongsoo Choi
Journal Article
Method Development
Microphysiological Systems
Neuronal Cell Cultures
MaxLab Live
MaxOne
Frontiers in Neuroscience
|
2022
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Recording Saltatory Conduction Along Sensory Axons Using a High-Density Microelectrode Array

Kenta Shimba, Takahiro Asahina, Koji Sakai, Kiyoshi Kotani, Yasuhiko Jimbo
Journal Article
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2022
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Downregulating α-synuclein in iPSC-derived dopaminergic neurons mimics electrophysiological phenotype of the A53T mutation

Philipp Hornauer, Gustavo Prack, Nadia Anastasi, Silvia Ronchi, Taehoon Kim, Christian Donner, Michele Fiscella, Karsten Borgwardt, Verdon Taylor, Ravi Jagasia, Damian Roqueiro, Andreas Hierlemann, Manuel Schröter
Preprint
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
arXiv
|
2022
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Design strategies for controlling neuron-connected robots using reinforcement learning

Haruto Sawada, Naoki Wake, Kazuhiro Sasabuchi, Jun Takamatsu, Hirokazu Takahashi, Katsushi Ikeuchi
Preprint
Microphysiological Systems
Biocomputing
Neuronal Cell Cultures
MaxOne
Frontiers in Neuroscience
|
2022
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Engineered Biological Neural Networks on High Density CMOS Microelectrode Arrays

Jens Duru, Joël Küchler, Stephan J. Ihle, Csaba Forró, Aeneas Bernardi, Sophie Girardin, Julian Hengsteler, Stephen Wheeler, János Vörös, Tobias Ruff
Journal Article
Microphysiological Systems
Neuronal Cell Cultures
MaxOne
Nature
|
2022
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Autism genes converge on asynchronous development of shared neuron classes

Bruna Paulsen, Silvia Velasco, Amanda J. Kedaigle, Martina Pigoni, Giorgia Quadrato, Anthony J. Deo, Xian Adiconis, Ana Uzquiano, Rafaela Sartore, Sung Min Yang, Sean K. Simmons, Panagiotis Symvoulidis, Kwanho Kim, Kalliopi Tsafou, Archana Podury, Catherine Abbate, Ashley Tucewicz, Samantha N. Smith, Alexandre Albanese, Lindy Barrett, Neville E. Sanjana, Xi Shi, Kwanghun Chung, Kasper Lage, Edward S. Boyden, Aviv Regev, Joshua Z. Levin, Paola Arlotta
Journal Article
Disease Modeling
Organoids
MaxLab Live
MaxOne
|
2022
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Multielectrode Arrays for Functional Phenotyping of Neurons from Induced Pluripotent Stem Cell Models of Neurodevelopmental Disorders

Fraser P. McCready, Sara Gordillo-Sampedro, Kartik Pradeepan, Julio Martinez-Trujillo, James Ellis
Journal Article
Disease Modeling
MaxOne
Physical Review Research
|
2021
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Unifying framework for information processing in stochastically driven dynamical systems

Tomoyuki Kubota, Hirokazu Takahashi, Kohei Nakajima
Journal Article
Biocomputing
Neuronal Cell Cultures
MaxOne
Toxins
|
2021
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Human-Relevant Sensitivity of iPSC-Derived Human Motor Neurons to BoNT/A1 and B1

Maren Schenke, Hélène-Christine Prause, Wiebke Bergforth, Adina Przykopanski, Andreas Rummel, Frank Klawonn, Bettina Seeger
Journal Article
Pharmacology & Toxicology
Neuronal Cell Cultures
MaxLab Live
MaxOne
Nature Communications
|
2021
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16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro

Maria Sundberg, Hannah Pinson, Richard S. Smith, Kellen D. Winden, Pooja Venugopal, Derek J. C. Tai, James F. Gusella, Michael E. Talkowski, Christopher A. Walsh, Max Tegmark, Mustafa Sahin
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
PLOS Computational Biology
|
2021
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Inhibitory neurons exhibit high controlling ability in the cortical microconnectome

Motoki Kajiwara, Ritsuki Nomura, Felix Goetze, Masanori Kawabata, Yoshikazu Isomura, Tatsuya Akutsu, Masanori Shimono
Journal Article
Functional Phenotyping
MaxOne
PLOS Computational Biology
|
2021
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Inhibitory neurons exhibit high controlling ability in the cortical microconnectome

Motoki Kajiwara, Ritsuki Nomura, Felix Goetze, Masanori Kawabata, Yoshikazu Isomura, Tatsuya Akutsu, Masanori Shimono
Journal Article
Functional Phenotyping
Brain Slices
MaxLab Live
MaxOne
IEEE Journal of Solid-State Circuits
|
2021
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Extracellular Recording of Entire Neural Networks Using a Dual-Mode Microelectrode Array With 19 584 Electrodes and High SNR

Xinyue Yuan, Andreas Hierlemann, Urs Frey
Journal Article
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Advanced Biology
|
2021
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Electrophysiological Phenotype Characterization of Human iPSC‐Derived Neuronal Cell Lines by Means of High‐Density Microelectrode Arrays

Silvia Ronchi, Alessio Paolo Buccino, Gustavo Prack, Sreedhar Saseendran Kumar, Manuel Schröter, Michele Fiscella, Andreas Hierlemann
Journal Article
Functional Phenotyping
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2020
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Different contrast encoding in ON and OFF visual pathways

Saad Idrees, Thomas A. Münch
Preprint
Retina
MaxOne
Cell Death & Disease
|
2020
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Corticotropin-releasing hormone (CRH) alters mitochondrial morphology and function by activating the NF-kB-DRP1 axis in hippocampal neurons

Chiara R. Battaglia, Silvia Cursano, Enrico Calzia, Alberto Catanese, Tobias M. Boeckers
Journal Article
Neuronal Cell Cultures
MaxLab Live
MaxTwo
Science Advances
|
2020
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A magnetically actuated microrobot for targeted neural cell delivery and selective connection of neural networks

Eunhee Kim, Sungwoong Jeon, Hyun-Kyu An, Mehrnoosh Kianpour, Seong-Woon Yu, Jin-young Kim, Jong-Cheol Rah, Hongsoo Choi
Journal Article
Neuronal Cell Cultures
MaxLab Live
MaxOne
Cell
|
2020
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Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution

Cameron S. Cowan, Magdalena Renner, Martina De Gennaro, Brigitte Gross-Scherf, David Goldblum, Yanyan Hou, Martin Munz, Tiago M. Rodrigues, Jacek Krol, Tamas Szikra, Rachel Cuttat, Annick Waldt, Panagiotis Papasaikas, Roland Diggelmann, Claudia P. Patino-Alvarez, Patricia Galliker, Stefan E. Spirig, Dinko Pavlinic, Nadine Gerber-Hollbach, Sven Schuierer, Aldin Srdanovic, Marton Balogh, Riccardo Panero, Akos Kusnyerik, Arnold Szabo, Michael B. Stadler, Selim Orgül, Simone Picelli, Pascal W. Hasler, Andreas Hierlemann, Hendrik P. N. Scholl, Guglielmo Roma, Florian Nigsch, Botond Roska
Journal Article
Pharmacology & Toxicology
Retina
Neuronal Cell Cultures
MaxOne
IEEE EMBC
|
2020
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MAPSYNE: Miniaturized micropipette system combined with high-density microelectrode arrays for automated manipulation of neuronal networks in-vitro

Chiara Ricci, Urs Frey, Marie Engelene J. Obien
Conference Paper
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MaxLab Live
MaxOne
Molecular Neurobiology
|
2020
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Layers II/III of Prefrontal Cortex in Df(h22q11)/+ Mouse Model of the 22q11.2 Deletion Display Loss of Parvalbumin Interneurons and Modulation of Neuronal Morphology and Excitability

Abdel-Rahman Al-Absi, Per Qvist, Samora Okujeni, Ahmad Raza Khan, Simon Glerup, Connie Sanchez, Jens R. Nyengaard
Journal Article
Brain Slices
MaxOne
|
2020
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Sleep as a default state of cortical and subcortical networks

Mojtaba Bandarabadi, Anne Vassalli, Mehdi Tafti
Journal Article
Neuronal Cell Cultures
MaxLab Live
MaxOne
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