Abstract
Details
- Capture robust, synchronized network activity: MaxTwo 24‑Well HD‑MEA recordings reveal consistent spontaneous firing, low‑noise extracellular signals, and synchronized population bursts across independent 3D InSight™ Human Neural Microtissues.
- Distinguish compound‑specific network responses: High‑resolution functional profiling captures distinct pharmacological effects, with kainic acid and 4‑AP enhancing network bursting, while isoguvacine and TTX suppress or abolish neuronal activity.
- Reveal distinct burst kinetics: Advanced MaxLab Live burst‑shape analysis resolves changes in burst onset, peak amplitude, and decay, differentiating the effects of kainic acid and 4‑AP beyond conventional network metrics.