MaxWell Webinar with Dr. Yoshiho Ikeuchi and Dr. Tomoya Duenki

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Date & Time

Wednesday, April 23, 2025 | 09:30 & 17:00 CEST

00:30 & 08:00 PDT | 03:30 & 11:00 EDT | 15:30 & 23:00 CST | 16:30 & 00:00 JST

Tags
MaxTwo
Functional Phenotyping
ETH Zurich HD-MEA
Organoids
Method Development

Webinar Hightlights

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The webinar covered

  • Inter-regional connectivity being key for complex brain functions
  • Neural organoid networks serving as in vitro models of inter-regional brain circuits
  • HD-MEAs enabling detailed analysis of organoid network activity and functional connectivity

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The webinar covered

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Agenda

Wednesday, April 23, 2025 | 09:30 & 17:00 CEST

Construction and Evaluation of Neural Organoid Networks and Circuits on High Density Microelectrode Arrays (HD-MEAs)

Prof. Dr. Yoshiho Ikeuchi, Dr. Tomoya Duenki, and Dr. Silvia Ronchi

Abstract

Inter-regional connections and networks are fundamental architectural motifs of the human brain, enabling the integration of neural circuits to generate complex functions. To investigate the mechanistic significance of such connections in neural circuit development, we propose in vitro models of inter-regional networks by constructing networks of multiple neural organoids on High-Density Microelectrode Arrays (HD-MEAs). HD-MEAs provide a powerful platform for recording and analyzing the spatiotemporal activity patterns of neural organoid networks, allowing us to examine functional connectivity in the inter-organoid networks. 

Abstract

Speakers

Prof. Dr. Yoshiho Ikeuchi

Institute of Industrial Science, The University of Tokyo (Japan)

Biography

After finishing Ph.D. study on RNA modifications at The University of Tokyo, Yoshiho Ikeuchi conducted post-doctoral research in molecular and cellular neuroscience at the Harvard Medical School and Washington University, St. Louis until 2014. After returning to Japan, he has been conducting research on functional interrogation and engineering of neural organoids at the Institute of Industrial Science, The University of Tokyo. 

Abstract

Dr. Tomoya Duenki

Institute of Industrial Science, The University of Tokyo (Japan)

Biography

Tomoya Duenki is a researcher at the Ikeuchi Lab, Institute of Industrial Science, The University of Tokyo, where he conducted his PhD studies. He holds a master’s degree in Biomedical Engineering from ETH Zurich and focusses on engineering techniques to improve studies using neural organoids.

Abstract

Dr. Silvia Ronchi

Senior Product Manager, MaxTwo | MaxWell Biosystems (Switzerland)

Biography

Dr. Silvia Ronchi is Product Manager and Senior Application Scientist at MaxWell Biosystems, where she leverages her scientific background and user support to guide new product development and strengthen existing solutions in in vitro electrophysiology. She earned a PhD in Neuroscience at ETH Zurich, focusing on electrophysiology with High-Density Microelectrode Arrays. Her doctoral work spanned retinal and primary neuron preparations and later iPSC-derived neuronal models to study neurodegenerative diseases such as Amyotrophic Lateral Sclerosis and Parkinson’s disease. Grounded in biomedical engineering and electrophysiology, Dr. Ronchi translates user needs into product features and drives innovation across MaxWell’s portfolio.

Abstract

Hosts

Dr. Marie Obien

CCO | MaxWell Biosystems (Switzerland)

Biography

Marie Obien is the Chief Commercial Officer (CCO) and a founding member of MaxWell Biosystems. Marie leads the company’s global commercial strategy, sales, business development, marketing, product management, channel partnerships, and customer success. A specialist in electrophysiology, Marie brings strong expertise in microelectrode arrays and complementary techniques, including the gold-standard patch-clamp method. She is the lead author of the most frequently cited review on MEA technology and has played a key role in shaping its adoption in neuroscience and drug discovery. Marie earned her PhD in Electrical Engineering from the Nara Institute of Science and Technology, Japan, and received neuroscience training as a postdoctoral researcher at RIKEN. She also completed the Global Innovation Program in Silicon Valley, focusing on business development and entrepreneurial leadership.

Recording available

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