MaxWell Webinar with Dr. Yoshiho Ikeuchi and Dr. Tomoya Duenki

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Date & Time

Wednesday, April 23, 2025 | 09:30 & 17:00 CEST

00:30 & 08:00 PDT | 03:30 & 11:00 EDT | 15:30 & 23:00 CST | 16:30 & 00:00 JST

Tags
HD-MEAs
Organoids
Method Development
MaxTwo
Functional Phenotyping

Webinar Hightlights

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The webinar covered

  • Inter-regional connectivity being key for complex brain functions
  • Neural organoid networks serving as in vitro models of inter-regional brain circuits
  • HD-MEAs enabling detailed analysis of organoid network activity and functional connectivity

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Agenda

Wednesday, April 23, 2025 | 09:30 & 17:00 CEST

Construction and Evaluation of Neural Organoid Networks and Circuits on High Density Microelectrode Arrays (HD-MEAs)

Prof. Dr. Yoshiho Ikeuchi, Dr. Tomoya Duenki, and Dr. Silvia Ronchi

Abstract

Inter-regional connections and networks are fundamental architectural motifs of the human brain, enabling the integration of neural circuits to generate complex functions. To investigate the mechanistic significance of such connections in neural circuit development, we propose in vitro models of inter-regional networks by constructing networks of multiple neural organoids on High-Density Microelectrode Arrays (HD-MEAs). HD-MEAs provide a powerful platform for recording and analyzing the spatiotemporal activity patterns of neural organoid networks, allowing us to examine functional connectivity in the inter-organoid networks. 

Abstract

Speakers

Prof. Dr. Yoshiho Ikeuchi

Institute of Industrial Science, The University of Tokyo (Japan)

Biography

After finishing Ph.D. study on RNA modifications at The University of Tokyo, Yoshiho Ikeuchi conducted post-doctoral research in molecular and cellular neuroscience at the Harvard Medical School and Washington University, St. Louis until 2014. After returning to Japan, he has been conducting research on functional interrogation and engineering of neural organoids at the Institute of Industrial Science, The University of Tokyo. 

Abstract

Dr. Tomoya Duenki

Institute of Industrial Science, The University of Tokyo (Japan)

Biography

Tomoya Duenki is a researcher at the Ikeuchi Lab, Institute of Industrial Science, The University of Tokyo, where he conducted his PhD studies. He holds a master’s degree in Biomedical Engineering from ETH Zurich and focusses on engineering techniques to improve studies using neural organoids.

Abstract

Dr. Silvia Ronchi

Product Manager & Senior Application Scientist | MaxWell Biosystems (Switzerland)

Biography

Dr. Silvia Ronchi is Product Manager and Senior Application Scientist at MaxWell Biosystems, where she leverages her scientific background and user support to guide new product development and strengthen existing solutions in in vitro electrophysiology. She earned a PhD in Neuroscience at ETH Zurich, focusing on electrophysiology with High-Density Microelectrode Arrays. Her doctoral work spanned retinal and primary neuron preparations and later iPSC-derived neuronal models to study neurodegenerative diseases such as Amyotrophic Lateral Sclerosis and Parkinson’s disease. Grounded in biomedical engineering and electrophysiology, Dr. Ronchi translates user needs into product features and drives innovation across MaxWell’s portfolio.

Abstract

Hosts

Marie Obien

CCO | MaxWell Biosystems (Switzerland)

Biography

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