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bioRxiv
|
2025
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Altered Protein Phosphorylation in a Novel Midbrain Organoid Model for Bipolar Disorder

Katharina Meyer, Matthew Woodworth, Maria Carolina Bittencourt Gonçalves, Michelle Yue, Hoor AlJandal, Shad Morton, Michael Lewandowski, Ninning Liu, Eric Zigon, Patrick Fortuna, Mariana Garcia-Corral, Bogdan Budnik, George M. Church, Jenny M. Tam
Preprint
Disease Modeling
Organoids
MaxLab Live
MaxTwo
bioRxiv
|
2025
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In vitro 2 In vivo : Bidirectional and High-Precision Generation of In Vitro and In Vivo Neuronal Spike Data

Masanori Shimono
Preprint
Brain Slices
MaxOne
bioRxiv
|
2025
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MAIS: an in-vitro sandbox enables adaptive neuromodulation via scalable neural interfaces

Haoman Chen, Fanxuan Chen, Xinyu Chen, Yang Liu, Junpeng Xu, Jiajun Li, Xueying Bao, Yuzhe Chen, Haojun Sun, Jiaju Jiang, Fangzhou Ye, Jianzhong Su, Yang Gen, Fangfu Ye, Zhouguang Wang, Liyu Liu, Saiyin Hexige, Xiaokun Li, Lixiang Ma, Jianwei Shuai
Preprint
Biocomputing
Neuronal Cell Cultures
MaxOne
bioRxiv
|
2025
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HIPPIE: A Multimodal Deep Learning Model for Electrophysiological Classification of Neurons

Jesus Gonzalez-Ferrer, Julian Lehrer, Hunter E. Schweiger, Jinghui Geng, Sebastian Hernandez, Francisco Reyes, Jess L. Sevetson, Sofie R. Salama, Mircea Teodorescu, David Haussler, Mohammed A. Mostajo-Radji
Preprint
Method Development
Brain Slices
MaxOne
bioRxiv
|
2025
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APP overexpression delays synaptic development and alters neuronal network properties

Fulin Ma, Himanshu Akolkar, Ryad Benosman, Karl Herrup
Preprint
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2025
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Induction and long-term maintenance of hindbrain-like neural stem cells in xeno- and basic fibroblast growth factor-free conditions

Ziadoon Al-Akashi, Denise Zujur, Nicholas Boyd-Gibbins, Nathalie Eileen Wiguna, Masato Nakagawa, Tetsuhiro Kikuchi, Asuka Morizane, Jun Takahashi, Makoto Ikeya
Preprint
Functional Phenotyping
Organoids
MaxLab Live
MaxOne
bioRxiv
|
2025
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Modeling Organoid Population Electrophysiology Dynamics

Matthew J. Roos, Diego Luna, Dowlette-Mary Alam El Din, Thomas Hartung, Lena Smirnova, Alex Proescher, Erik C. Johnson
Preprint
Biocomputing
Organoids
MaxTwo
bioRxiv
|
2025
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Chronic social defeat causes dysregulation of systemic glucose metabolism via the cerebellar fastigial nucleus

Taiga Ishimoto, Takashi Abe, Yuko Nakamura, Tomonori Tsuyama, Kunio Kondoh, Naoto Kajitani, Kaede Yoshida, Yuichi Takeuchi, Kan X. Kato, Shucheng Xu, Maru Koduki, Momoka Ichimura, Takito Itoi, Kenta Shimba, Yoshifumi Yamaguchi, Masabumi Minami, Shinsuke Koike, Kiyoto Kasai, Jessica J. Ye, Minoru Takebayashi, Kazuya Yamagata, Chitoku Toda
Preprint
Disease Modeling
Pharmacology & Toxicology
Brain Slices
MaxOne
Neuro-Oncology
|
2025
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Targeting PGE2 mediated senescent neuron improves tumour therapy

Jianyi Zhao, Linshi Wu, Gang Cai, Dan Ou, Keman Liao, Jian Yang, Li Zhou, Renhua Huang, Shukai Lin, Xi Huang, Qi Lv, Juxiang Chen, Lu Cao, Jiayi Chen, Yingying Lin
Journal Article
Disease Modeling
Functional Phenotyping
Neuronal Cell Cultures
MaxLab Live
MaxOne
Advanced Functional Materials
|
2025
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An Implantable Biohybrid Neural Interface Toward Synaptic Deep Brain Stimulation

Léo Sifringer, Alex Fratzl, Blandine F. Clément, Parth Chansoria, Leah S. Mönkemöller, Jens Duru, Stephan J. Ihle, Simon Steffens, Anna Beltraminelli, Eylul Ceylan, Julian Hengsteler, Benedikt Maurer, Sean M. Weaver, Christina M. Tringides, Katarina Vulić, Srinivas Madduri, Marcy Zenobi-Wong, Botond Roska, János Vörös, Tobias Ruff
Journal Article
Microphysiological Systems
Retina
Organoids
MaxOne
|
2025
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Flexible and stretchable bioelectronics for organoids

Jaeyong Lee, Jia Liu
Journal Article
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bioRxiv
|
2025
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Self-organization of high-dimensional geometry of neural activity in culture

Asahi Nakamuta, Dai Akita, He Zhang, Yuta Kawahara, Hirokazu Takahashi, Jun-nosuke Teramae
Preprint
Neuronal Cell Cultures
MaxOne
bioRxiv
|
2025
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Repetitive stimulation modifies network characteristics of neural organoid circuits

Siu Yu A. Chow, Huaruo Hu, Tomoya Duenki, Takuya Asakura, Sota Sugimura, Yoshiho Ikeuchi
Preprint
Organoids
MaxLab Live
MaxOne
bioRxiv
|
2025
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Engineered biological neural networks as basic logic operators

Joël Küchler, Katarina Vulić, Haotian Yao, Christian Valmaggia, Stephan Johannes Ihle, Sean Weaver, Janos Vörös
Preprint
Microphysiological Systems
Neuronal Cell Cultures
MaxOne
Stem Cell Reports
|
2025
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Swift induction of human spinal lower motor neurons and robust ALS cell screening via single-cell imaging

Selena Setsu, Satoru Morimoto, Shiho Nakamura, Fumiko Ozawa, Kagistia Hana Utami, Ayumi Nishiyama, Naoki Suzuki, Masashi Aoki, Yukio Takeshita, Yukihide Tomari, Hideyuki Okano
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
Journal of Neurochemistry
|
2025
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Regulation of Dendrite and Dendritic Spine Formation by TCF20

Ersilia Vinci, Stefania Beretta, Veronica Colombo, Antonio Zippo, Alberto Catanese, Christoph Wiegreffe, Stefan Britsch, Tobias Boeckers, Chiara Verpelli, Carlo Sala
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxTwo
bioRxiv
|
2025
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Recreating coronary vascularization and sympathetic innervation of myocardium on a human pluripotent stem cell-derived heart organoid

Mariana A. Branco, Mafalda Marques Nunes, Ana Luísa Rayagra, Miguel F. Tenreiro, Joaquim M.S. Cabral, Maria Margarida Diogo
Preprint
Functional Phenotyping
Organoids
MaxTwo
Frontiers in Neuroscience
|
2025
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Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders

Ziqin Yang, Nicole A. Teaney, Elizabeth D. Buttermore, Mustafa Sahin, Wardiya Afshar-Saber
Journal Article
No items found.
MaxOne
Advanced Healthcare Materials
|
2025
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Insulative Compression of Neuronal Tissues on Microelectrode Arrays by Perfluorodecalin Enhances Electrophysiological Measurements

Tomoya Duenki, Yoshiho Ikeuchi
Journal Article
Microphysiological Systems
Retina
Neuronal Cell Cultures
Organoids
MaxOne
arXiv
|
2025
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A Computational Perspective on NeuroAI and Synthetic Biological Intelligence

Dhruvik Patel, Md Sayed Tanveer, Jesus Gonzalez-Ferrer, Alon Loeffler, Brett J. Kagan, Mohammed A. Mostajo-Radji, Ge Wang
Preprint
Method Development
Biocomputing
No items found.
arXiv
|
2025
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Encoding Tactile Stimuli for Organoid Intelligence in Braille Recognition

Tianyi Liu, Hemma Philamore, Benjamin Ward-Cherrier
Preprint
Biocomputing
Organoids
MaxTwo
Lab on a Chip
|
2025
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Seamless integration of CMOS microsensors into open microfluidic systems

Raziyeh Bounik, Alex E Landolt, Jihyun Lee, Vijay Viswam, Fernando Cardes, Mario M Modena, Andreas Hierlemann
Journal Article
Method Development
Microphysiological Systems
No items found.
PLOS ONE
|
2024
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Theoretical analysis of neuronal network’s response under different stimulus

Haosen Xue, Zeying Lu, Yueheng Lan, Lili Gui, Xiaojuan Sun
Journal Article
Functional Phenotyping
Neuronal Cell Cultures
MaxOne
arXiv
|
2024
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Starting a Synthetic Biological Intelligence Lab from Scratch

Md Sayed Tanveer, Dhruvik Patel, Hunter E. Schweiger, Kwaku Dad Abu-Bonsrah, Brad Watmuff, Azin Azadi, Sergey Pryshchep, Karthikeyan Narayanan, Christopher Puleo, Kannathal Natarajan, Mohammed A. Mostajo-Radji, Brett J. Kagan, Ge Wang
Preprint
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2024
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Multiscale Cloud-Based Pipeline for Neuronal Electrophysiology Analysis and Visualization

Jinghui Geng, Kateryna Voitiuk, David F. Parks, Ash Robbins, Alex Spaeth, Jessica L. Sevetson, Sebastian Hernandez, Hunter E. Schweiger, John P. Andrews, Spencer T. Seiler, Matthew A. T. Elliott, Edward F. Chang, Tomasz J. Nowakowski, Rob Currie, Mohammed A. Mostajo-Radji, David Haussler, Tal Sharf, Sofie R. Salama, Mircea Teodorescu
Preprint
Disease Modeling
Neuronal Cell Cultures
Organoids
Brain Slices
MaxOne
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