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Journal of Neural Engineering
|
2022
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Inferring monosynaptic connections from paired dendritic spine Ca2+ imaging and large-scale recording of extracellular spiking

Xiaohan Xue, Alessio Paolo Buccino, Sreedhar Saseendran Kumar, Andreas Hierlemann, Julian Bartram
Journal Article
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Molecular and Cellular Neuroscience
|
2022
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Df (h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus

Abdel-Rahman Al-Absi, Sakeerthi Kethees Thambiappa, Ahmad Raza Khan, Simon Glerup, Connie Sanchez, Anne M Landau, Jens R Nyengaard
Journal Article
Disease Modeling
Brain Slices
MaxOne
bioRxiv
|
2022
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A multi-modal fitting approach to construct single-neuron models with patch clamp and high-density microelectrode arrays

Alessio Paolo Buccino, Tanguy Damart, Julian Bartram, Darshan Mandge, Xiaohan Xue, Mickael Zbili, Tobias Gänswein, Aurélien Jaquier, Vishalini Emmenegger, Henry Markram, Andreas Hierlemann, Werner Van Geit
Preprint
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Nature Communications
|
2022
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Functional neuronal circuitry and oscillatory dynamics in human brain organoids

Tal Sharf, Tjitse van der Molen, Stella M. K. Glasauer, Elmer Guzman, Alessio P. Buccino, Gabriel Luna, Zhuowei Cheng, Morgane Audouard, Kamalini G. Ranasinghe, Kiwamu Kudo, Srikantan S. Nagarajan, Kenneth R. Tovar, Linda R. Petzold, Andreas Hierlemann, Paul K. Hansma, Kenneth S. Kosik
Journal Article
Organoids
MaxLab Live
MaxOne
Communications Biology
|
2022
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Suppression without inhibition: how retinal computation contributes to saccadic suppression

Saad Idrees, Matthias-Philipp Baumann, Maria M. Korympidou, Timm Schubert, Alexandra Kling, Katrin Franke, Ziad M. Hafed, Felix Franke, Thomas A. Münch
Journal Article
Functional Phenotyping
Retina
MaxLab Live
MaxOne
Brain Communications
|
2022
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P97/VCP ATPase inhibitors can rescue p97 mutation-linked motor neuron degeneration

F Wang, S Li, T Y Wang, G A Lopez, I Antoshechkin, T F Chou
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxTwo
MRS Bulletin
|
2022
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Functional imaging of brain organoids using high-density microelectrode arrays

Manuel Schröter, Congwei Wang, Marco Terrigno, Philipp Hornauer, Ziqiang Huang, Ravi Jagasia, Andreas Hierlemann
Journal Article
Organoids
MaxLab Live
MaxOne
MaxTwo
bioRxiv
|
2022
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Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells

Jax H. Xu, Yao Yao, Fenyong Yao, Jiehui Chen, Meishi Li, Xianfa Yang, Sheng Li, Fangru Lu, Ping Hu, Shuijin He, Guangdun Peng, Naihe Jing
Preprint
Functional Phenotyping
Neuronal Cell Cultures
MaxLab Live
MaxOne
Frontiers in Molecular Neuroscience
|
2022
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Aging-dependent altered transcriptional programs underlie activity impairments in human C9orf72-mutant motor neurons

Daniel Sommer, Sandeep Rajkumar, Mira Seidel, Amr Aly, Albert Ludolph, Ritchie Ho, Tobias M Boeckers, Alberto Catanese
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2022
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Automated detection of extracellular action potentials from single neurons

Zhuowei Cheng, Elmer Guzman, Tjitse van der Molen, Tal Sharf, Paul K. Hansma, Kenneth S. Kosik, Linda Petzold, Kenneth R. Tovar
Preprint
Neuronal Cell Cultures
MaxLab Live
MaxOne
Small
|
2022
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A Biodegradable Magnetic Microrobot Based on Gelatin Methacrylate for Precise Delivery of Stem Cells with Mass Production Capability

Seungmin Noh, Sungwoong Jeon, Eunhee Kim, Untaek Oh, Danbi Park, Sun Hwa Park, Sung Won Kim, Salvador Pané, Bradley J. Nelson, Jin-young Kim, Hongsoo Choi
Journal Article
Method Development
Microphysiological Systems
Neuronal Cell Cultures
MaxLab Live
MaxOne
Frontiers in Neuroscience
|
2022
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Recording Saltatory Conduction Along Sensory Axons Using a High-Density Microelectrode Array

Kenta Shimba, Takahiro Asahina, Koji Sakai, Kiyoshi Kotani, Yasuhiko Jimbo
Journal Article
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2022
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Downregulating α-synuclein in iPSC-derived dopaminergic neurons mimics electrophysiological phenotype of the A53T mutation

Philipp Hornauer, Gustavo Prack, Nadia Anastasi, Silvia Ronchi, Taehoon Kim, Christian Donner, Michele Fiscella, Karsten Borgwardt, Verdon Taylor, Ravi Jagasia, Damian Roqueiro, Andreas Hierlemann, Manuel Schröter
Preprint
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
arXiv
|
2022
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Design strategies for controlling neuron-connected robots using reinforcement learning

Haruto Sawada, Naoki Wake, Kazuhiro Sasabuchi, Jun Takamatsu, Hirokazu Takahashi, Katsushi Ikeuchi
Preprint
Microphysiological Systems
Neurocomputing
Neuronal Cell Cultures
MaxOne
Frontiers in Neuroscience
|
2022
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Engineered Biological Neural Networks on High Density CMOS Microelectrode Arrays

Jens Duru, Joël Küchler, Stephan J. Ihle, Csaba Forró, Aeneas Bernardi, Sophie Girardin, Julian Hengsteler, Stephen Wheeler, János Vörös, Tobias Ruff
Journal Article
Microphysiological Systems
Neuronal Cell Cultures
MaxOne
Nature
|
2022
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Autism genes converge on asynchronous development of shared neuron classes

Bruna Paulsen, Silvia Velasco, Amanda J. Kedaigle, Martina Pigoni, Giorgia Quadrato, Anthony J. Deo, Xian Adiconis, Ana Uzquiano, Rafaela Sartore, Sung Min Yang, Sean K. Simmons, Panagiotis Symvoulidis, Kwanho Kim, Kalliopi Tsafou, Archana Podury, Catherine Abbate, Ashley Tucewicz, Samantha N. Smith, Alexandre Albanese, Lindy Barrett, Neville E. Sanjana, Xi Shi, Kwanghun Chung, Kasper Lage, Edward S. Boyden, Aviv Regev, Joshua Z. Levin, Paola Arlotta
Journal Article
Disease Modeling
Organoids
MaxLab Live
MaxOne
Physical Review Research
|
2021
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Unifying framework for information processing in stochastically driven dynamical systems

Tomoyuki Kubota, Hirokazu Takahashi, Kohei Nakajima
Journal Article
Neurocomputing
Neuronal Cell Cultures
MaxOne
Toxins
|
2021
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Human-Relevant Sensitivity of iPSC-Derived Human Motor Neurons to BoNT/A1 and B1

Maren Schenke, Hélène-Christine Prause, Wiebke Bergforth, Adina Przykopanski, Andreas Rummel, Frank Klawonn, Bettina Seeger
Journal Article
Pharmacology & Toxicology
Neuronal Cell Cultures
MaxLab Live
MaxOne
Nature Communications
|
2021
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16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro

Maria Sundberg, Hannah Pinson, Richard S. Smith, Kellen D. Winden, Pooja Venugopal, Derek J. C. Tai, James F. Gusella, Michael E. Talkowski, Christopher A. Walsh, Max Tegmark, Mustafa Sahin
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
PLOS Computational Biology
|
2021
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Inhibitory neurons exhibit high controlling ability in the cortical microconnectome

Motoki Kajiwara, Ritsuki Nomura, Felix Goetze, Masanori Kawabata, Yoshikazu Isomura, Tatsuya Akutsu, Masanori Shimono
Journal Article
Functional Phenotyping
Brain Slices
MaxLab Live
MaxOne
IEEE Journal of Solid-State Circuits
|
2021
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Extracellular Recording of Entire Neural Networks Using a Dual-Mode Microelectrode Array With 19 584 Electrodes and High SNR

Xinyue Yuan, Andreas Hierlemann, Urs Frey
Journal Article
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Advanced Biology
|
2021
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Electrophysiological Phenotype Characterization of Human iPSC‐Derived Neuronal Cell Lines by Means of High‐Density Microelectrode Arrays

Silvia Ronchi, Alessio Paolo Buccino, Gustavo Prack, Sreedhar Saseendran Kumar, Manuel Schröter, Michele Fiscella, Andreas Hierlemann
Journal Article
Functional Phenotyping
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2020
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Different contrast encoding in ON and OFF visual pathways

Saad Idrees, Thomas A. Münch
Preprint
Retina
MaxOne
Cell Death & Disease
|
2020
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Corticotropin-releasing hormone (CRH) alters mitochondrial morphology and function by activating the NF-kB-DRP1 axis in hippocampal neurons

Chiara R. Battaglia, Silvia Cursano, Enrico Calzia, Alberto Catanese, Tobias M. Boeckers
Journal Article
Neuronal Cell Cultures
MaxLab Live
MaxTwo
Science Advances
|
2020
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A magnetically actuated microrobot for targeted neural cell delivery and selective connection of neural networks

Eunhee Kim, Sungwoong Jeon, Hyun-Kyu An, Mehrnoosh Kianpour, Seong-Woon Yu, Jin-young Kim, Jong-Cheol Rah, Hongsoo Choi
Journal Article
Neuronal Cell Cultures
MaxLab Live
MaxOne
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