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Observing the activity of human-derived neurons in health and in disease
The combination of two technologies—induced pluripotent stem cells and high-density microelectrode arrays—offers an unprecedented platform to study human brain activity in detail outside the body. Back in 2006, Prof. Yamanaka and colleagues revealed a technique to reprogram adult skin cells into embryonic-like cells called induced pluripotent stem cells or iPSCs. This Nobel Prize winning technology enables access to human neurons derived from adult blood or skin cells in a high-throughput manner, thus opening up the possibilities to study neurological…
MaxWell Monthly Must-Reads (March 2021)
It is already time for the last MaxWell Monthly Must-Reads edition of the first quarter of 2021. Last month we focused on the topic of Simulation of extracellular neuronal spiking activity. In this edition we will focus on 3D Neural-Interfaces, and as always we selected five papers that we think are worth reading. Enjoy! Three-dimensional, multifunctional neural interfaces for cortical spheroids and engineered assembloids. by Park, Y., Franz, C. K., Ryu, H., Luan, H., Cotton, K. Y., Kim, J. U.,…
MaxWell Monthly Must-Reads (February 2021)
Welcome to our MaxWell Monthly Must-Reads blog. As mentioned in our previous edition, we will, this year again, share with you 12 new monthly must-reads! Each month we will choose a theme and select five papers that we think are worth reading. Last month we focused on the topic of Functional Connectivity in Neuronal Networks. For our second edition, we are featuring the Simulation of extracellular neuronal spiking activity. High-density microelectrode array (HD-MEA) devices feature hundreds to thousands of electrodes…
MaxWell Monthly Must-Reads (January 2021)
Welcome to our MaxWell Monthly Must-Reads blog. A new year also means new publications to highlight and new topics to discover. This year as well, for our monthly must-reads, we will choose a theme per month and select five papers that we think are worth reading. Last year we covered a range of topics from Human iPSC-Derived Neurons to a special COVID-19 edition called Neurons and Viruses. In our first edition of 2021, we have decided to focus on Functional…
MaxWell Biosystems Completes CHF 4 million Series A Financing Round
Zurich, Switzerland, 16 December 2020 – MaxWell Biosystems AG, a spin-off from ETH Zürich founded in 2016 announced today the closing of a CHF 4 million Series A financing round to further industrialize and scale-up the production of their consumables, so called multiwell high-density microelectrode array (HD-MEA) plates. Such scale-up will enable the customers of MaxWell Biosystems in the pharmaceutical industry to run functional drug screenings at a higher throughput and ultimately contribute to accelerate the development of drugs targeting…