Publications

Publications

 


Selected Publications

Mueller2015

High-resolution CMOS MEA platform to study neurons at subcellular, cellular, and network levels

Presenting measurements of neuronal preparations with a novel CMOS-based microelectrode array at high-spatiotemporal-resolution on subcellular, cellular, and network level.

J. Müller, M. Ballini, P. Livi, Y. Chen, M. Radivojevic, A. Shadmani, V. Viswam, I. L. Jones, M. Fiscella, R. Diggelmann, A. Stettler, U. Frey, D. J. Bakkum, and A. Hierlemann, “High-resolution CMOS MEA platform to study neurons at subcellular, cellular, and network levels,” Lab Chip, vol. 15, no. 13, pp. 2767–2780, May 2015.

Obien2014

Revealing Neuronal Function through Microelectrode Array Recordings

Reviewing the current understanding of microelectrode signals and the techniques for analyzing them, with focus on the ongoing advancements in microelectrode technology (in vivo and in vitro) and recent advanced microelectrode array measurement methods that facilitate the understanding of single neurons and network function.

M. E. J. Obien, K. Deligkaris, T. Bullmann, D. J. Bakkum, and U. Frey, “Revealing Neuronal Function through Microelectrode Array Recordings,” Front. Neurosci., 8:423, Jan 2015.

Ballini2014

A 1024-Channel CMOS Microelectrode Array With 26,400 Electrodes for Recording and Stimulation of Electrogenic Cells In Vitro

A high-resolution CMOS-based microelectrode array featuring 1,024 low-noise readout channels, 26,400 electrodes at a density of 3,265 electrodes per mm2, including on-chip 10bit ADCs and consuming only 75 mW.

M. Ballini, J. Muller, P. Livi, Y. Chen, U. Frey, A. Stettler, A. Shadmani, V. Viswam, I. L. Jones, D. Jackel, M. Radivojevic, M. K. Lewandowska, W. Gong, M. Fiscella, D. J. Bakkum, F. Heer, and A. Hierlemann, “A 1024-Channel CMOS Microelectrode Array With 26,400 Electrodes for Recording and Stimulation of Electrogenic Cells In Vitro,” IEEE Journal of Solid-State Circuits, vol. 49, no. 11, pp. 2705-2719, 2014.

Bakkum2013ncomm

Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites

Demonstrating a method to electrically visualize action potential propagation on axons and revealing
large variations in velocity.

D. J. Bakkum, U. Frey, M. Radivojevic, T. L. Russell, J. Muller, M. Fiscella, H. Takahashi, and A. Hierlemann, “Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites,” Nature Communications, 4:2181, Jul 2013.

Frey08BioSensors

Microelectronic System for High-Resolution Mapping of Extracellular Electric Fields Applied to Brain Slices

Recording and modeling extracellular action potentials of Purkinje cells at subcellular resolution.

U. Frey, U. Egert, F. Heer, S. Hafizovic, and A. Hierlemann, “Microelectronic System for High-Resolution Mapping of Extracellular Electric Fields Applied to Brain Slices,” Biosensors and Bioelectronics, vol. 24, no. 7, pp. 2191-2198, 2009.

SanchezBustamante07NRC

Modulation of Cardiomyocyte Electrical Properties Using Regulated Bone Morphogenetic Protein-2 Expression

Controlling BMP-2 expression to modulate the electrophysiological properties of cardiomyocytes using an HD-MEA for detailed monitoring.

C. D. Sanchez-Bustamante, U. Frey, J. M. Kelm, A. Hierlemann, and M. Fussenegger,
“Modulation of Cardiomyocyte Electrical Properties Using Regulated Bone Morphogenetic Protein-2 Expression,” Tissue Engineering Part A, vol. 14, no. 12, pp. 1969-1988, 2008.


All Publications

61 entries « 1 of 2 »

2019

Accurate signal-source localization in brain slices by means of high-density microelectrode arrays

Obien, Marie Engelene J; Hierlemann, Andreas; Frey, Urs

Accurate signal-source localization in brain slices by means of high-density microelectrode arrays Journal Article

Scientific Reports, 9 (788), 2019.

Abstract | Links | BibTeX | Tags: Brain Slice

Stimulation and Artifact-suppression Techniques for in-vitro High-density Microelectrode Array Systems.

Shadmani, Amir; Viswam, Vijay; Chen, Yihui; Bounik, Raziyeh; Dragas, Jelena; Radivojevic, Milos; Geissler, Sydney; Sitnikov, Sergey; Muller, Jan; Hierlemann, Andreas

Stimulation and Artifact-suppression Techniques for in-vitro High-density Microelectrode Array Systems. Journal Article

IEEE Transactions on Biomedical Engineering, 2019.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA

2018

The Axon Initial Segment is the Dominant Contributor to the Neuron's Extracellular Electrical Potential Landscape

Bakkum, Douglas J; Obien, Marie Engelene J; Radivojevic, Milos; Jäckel, David; Frey, Urs; Takahashi, Hirokazu; Hierlemann, Andreas

The Axon Initial Segment is the Dominant Contributor to the Neuron's Extracellular Electrical Potential Landscape Journal Article

Advanced Biosystems, 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA

Long-term high-density extracellular recordings enable studies of muscle cell physiology and pathology

Lewandowska, Marta K; Bogatikov, Evgenii; Hierlemann, Andreas; Punga, Anna Rostedt

Long-term high-density extracellular recordings enable studies of muscle cell physiology and pathology Conference

Contribution 700.13 , Society for Neuroscience (SfN) Meeting San Diego, CA, USA, 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Physiology

Investigating the analog modulation of action-potential waveforms in axonal arbors of cortical neurons using whole-cell patch-clamp recordings and high-density microelectrode arrays

Emmenegger, Vishalini; Bartram, Julian; Sitnikov, Sergey; Hierlemann, Andreas

Investigating the analog modulation of action-potential waveforms in axonal arbors of cortical neurons using whole-cell patch-clamp recordings and high-density microelectrode arrays Conference

Contribution 203.05 , Society for Neuroscience (SfN) Meeting, San Diego, CA, USA, 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA

Single-neuron sub-cellular-resolution electrical stimulation with high-density microelectrode arrays

Ronchi, Silvia; Fiscella, Michele; Marchetti, Camilla; Viswam, Vijay; Müller, Jan; Frey, Urs; Hierlemann, Andreas

Single-neuron sub-cellular-resolution electrical stimulation with high-density microelectrode arrays Conference

Contribution 174.05 , Society for Neuroscience (SfN) Meeting San Diego, CA, USA, 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Stimulation

Lewandowska, Marta K; Bogatikov, Evgenii; Hierlemann, Andreas; Punga, Anna Rostedt

Long-Term High-Density Extracellular Recordings Enable Studies of Muscle Cell Physiology Journal Article

Frontiers in Physiology, 9 , 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Muscle

Automatic Spike Sorting Algorithm for High-Density Microelectrode Arrays

Diggelmann, Roland; Fiscella, Michele; Hierlemann, Andreas; Franke, Felix

Automatic Spike Sorting Algorithm for High-Density Microelectrode Arrays Journal Article

Journal of Neurophysiology, 120 (4), 2018.

Abstract | Links | BibTeX | Tags: MEA Technology

Single-cell electrical stimulation with CMOS-based high-density microelectrode arrays

Ronchi, Silvia; Fiscella, Michele; Muller, Jan; Viswam, Vijay; Frey, Urs; Hierlemann, Andreas

Single-cell electrical stimulation with CMOS-based high-density microelectrode arrays Conference

11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting) Reutlingen, Germany, 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Stimulation

Comparison of axonal-conduction velocity in developing primary cells and human iPSC-derived neurons

Obien, Marie Engelene J; Zorzi, Giulio; Fiscella, Michele; Leary, Noelle; Hierlemann, Andreas

Comparison of axonal-conduction velocity in developing primary cells and human iPSC-derived neurons Conference

11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting) Reutlingen, Germany, 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, MaxOne

Automatic extraction of axonal arbor morphology applied to h-iPSC-derived neurons

Zorzi, Giulio; Obien, Marie Engelene J; Fiscella, Michele; Leary, Noelle; Hierlemann, Andreas

Automatic extraction of axonal arbor morphology applied to h-iPSC-derived neurons Conference

11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting) Reutlingen, Germany, 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, MaxOne

COMSOL modeling of an integrated impedance sensor in a hanging-drop platform

Bounik, Raziyeh; Gusmaroli, Massimiliano; Viswam, Vijay; Modena, Mario M; Hierlemann, Andreas

COMSOL modeling of an integrated impedance sensor in a hanging-drop platform Conference

11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting) Reutlingen, Germany, 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Microtissue

Dual-mode Microelectrode Array with 20k-electrodes and High SNR for High-Throughput Extracellular Recording and Stimulation

Yuan, Xinyue; Hierlemann, Andreas; Frey, Urs

Dual-mode Microelectrode Array with 20k-electrodes and High SNR for High-Throughput Extracellular Recording and Stimulation Conference

11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting) Reutlingen, Germany, 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Stimulation

How diverse retinal functions arise from feedback at the first visual synapse

da Drinnenberg Antonia; Franke, Felix; Morikawa Rei Jüttner; Hillier Daniel; Hantz Peter; Hierlemann Andreas; Azeredo Silveira Rava; Roska Botond K;

How diverse retinal functions arise from feedback at the first visual synapse Journal Article

Neuron, 99 (1), pp. 117-134, 2018.

Abstract | Links | BibTeX | Tags: Retina

The axon initial segment drives the neuron's extracellular action potential

Bakkum Douglas J; Radivojevic, Milos; Obien Marie Engelene; Jaeckel David; Frey Urs; Takahashi Hirokazu; Hierlemann Andreas

The axon initial segment drives the neuron's extracellular action potential Journal Article

bioRxiv, pp. 1-30, 2018.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA

2017

Tracking individual action potentials throughout mammalian axonal arbors

Radivojevic, Milos; Franke, Felix; Altermatt, Michael; Müller, Jan; Hierlemann, Andreas; Bakkum, Douglas J

Tracking individual action potentials throughout mammalian axonal arbors Journal Article

eLife, 6 , pp. 1-23, 2017, ISSN: 2050-084X.

Abstract | Links | BibTeX | Tags: Data Analysis, ETH-CMOS-MEA, Neuronal Networks, Stimulation

Locally embedded presages of global network bursts

Tajima Satohiro; Mita, Takeshi; Bakkum Douglas Takahashi Hirokazu; Toyoizumi Taro J;

Locally embedded presages of global network bursts Journal Article

National Academy of Sciences, pp. 1-6, 2017, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: Neuronal Networks

Large-scale mapping of cortical synaptic projections with extracellular electrode arrays

Shein-Idelson, Mark; Pammer, Lorenz; Hemberger, Mike; Laurent, Gilles

Large-scale mapping of cortical synaptic projections with extracellular electrode arrays Journal Article

Nature Methods, 14 (9), pp. 882–889, 2017, ISSN: 1548-7091.

Abstract | Links | BibTeX | Tags: Brain Slice, MaxOne, Neuronal Networks

Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex

Hillier, Daniel; Fiscella, Michele; Drinnenberg, Antonia; Trenholm, Stuart; Rompani, Santiago B; Raics, Zoltan; Katona, Gergely; Jüttner, Josephine; Hierlemann, Andreas; Rozsa, Balazs; Roska, Botond

Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex Journal Article

Nature Neuroscience, 20 (7), pp. 960–968, 2017, ISSN: 1097-6256.

Abstract | Links | BibTeX | Tags: MaxOne, Retina

Network Analysis Of High-Density Microelectrode Recordings

Bullmann Torsten; Radivojevic, Milos; Huber Stefan Deligkaris Kosmas; Hierlemann Andreas; Frey Urs T:

Network Analysis Of High-Density Microelectrode Recordings Journal Article

bioRxiv , (139436), pp. 1-23, 2017.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA

A Multi-Functional Microelectrode Array Featuring 59760 Electrodes, 2048 Electrophysiology Channels, Stimulation, Impedance Measurement and Neurotransmitter Detection Channels

Dragas, Jelena; Viswam, Vijay; Shadmani, Amir; Chen, Yihui; Bounik, Raziyeh; Stettler, Alexander; Radivojevic, Milos; Geissler, Sydney; Obien, Marie Engelene J; Müller, Jan; Hierlemann, Andreas

A Multi-Functional Microelectrode Array Featuring 59760 Electrodes, 2048 Electrophysiology Channels, Stimulation, Impedance Measurement and Neurotransmitter Detection Channels Journal Article

IEEE journal of solid-state circuits, 52 (6), pp. 1576-1590, 2017, ISSN: 0018-9200.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, MEA Technology

Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration

Jäckel, David; Bakkum, Douglas J; Russell, Thomas L; Müller, Jan; Radivojevic, Milos; Frey, Urs; Franke, Felix; Hierlemann, Andreas

Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration Journal Article

Scientific Reports, 7 (1), pp. 978, 2017, ISSN: 2045-2322.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Neuronal Networks

2016

Development of neural population activity toward self-organized criticality

Yada, Yuichiro; Mita, Takeshi; Sanada, Akihiro; Yano, Ryuichi; Kanzaki, Ryohei; Bakkum, Douglas J; Hierlemann, Andreas; Takahashi, Hirokazu

Development of neural population activity toward self-organized criticality Journal Article

Neuroscience, 343 , pp. 55-65, 2016, ISSN: 0306-4522.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Neuronal Networks

Multiple single-unit long-term tracking on organotypic hippocampal slices using high-density microelectrode arrays

Gong, Wei; Sencar, Jure; Bakkum, Douglas J; Jäckel, David; Obien, Marie Engelene J; Radivojevic, Milos; Hierlemann, Andreas

Multiple single-unit long-term tracking on organotypic hippocampal slices using high-density microelectrode arrays Journal Article

Frontiers in Neuroscience, 10 , pp. 1-16, 2016, ISSN: 1662453X.

Abstract | Links | BibTeX | Tags: Brain Slice, ETH-CMOS-MEA

Extracellularly Recorded Somatic and Neuritic Signal Shapes and Classification Algorithms for High-Density Microelectrode Array Electrophysiology

Deligkaris, Kosmas; Bullmann, Torsten; Frey, Urs

Extracellularly Recorded Somatic and Neuritic Signal Shapes and Classification Algorithms for High-Density Microelectrode Array Electrophysiology Journal Article

Frontiers in Neuroscience, 10 , pp. 421, 2016, ISSN: 1662-453X.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Neuronal Networks

Electrical Identification and Selective Microstimulation of Neuronal Compartments Based on Features of Extracellular Action Potentials

Radivojevic, Milos; Jäckel, David; Altermatt, Michael; Müller, Jan; Viswam, Vijay; Hierlemann, Andreas; Bakkum, Douglas J

Electrical Identification and Selective Microstimulation of Neuronal Compartments Based on Features of Extracellular Action Potentials Journal Article

Scientific Reports, 6 (1), pp. 1-20, 2016, ISSN: 2045-2322.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Neuronal Networks, Stimulation

Cortical axons, isolated in channels, display activity-dependent signal modulation as a result of targeted stimulation

Lewandowska, Marta K; Radivojevic, Milos; Jäckel, David; Müller, Jan; Hierlemann, Andreas

Cortical axons, isolated in channels, display activity-dependent signal modulation as a result of targeted stimulation Journal Article

Frontiers in Neuroscience, 10 , pp. 83, 2016, ISSN: 1662453X.

Abstract | Links | BibTeX | Tags: MaxOne, Neuronal Networks, u-Tunnels

Structures of Neural Correlation and How They Favor Coding

Franke, Felix; Fiscella, Michele; Sevelev, Maksim; Roska, Botond; Hierlemann, Andreas; Azeredo da Silveira, Rava

Structures of Neural Correlation and How They Favor Coding Journal Article

Neuron, 89 (2), pp. 409-422, 2016, ISSN: 10974199.

Abstract | Links | BibTeX | Tags: Data Analysis, ETH-CMOS-MEA, Neuronal Networks, Retina

Congenital Nystagmus Gene FRMD7 Is Necessary for Establishing a Neuronal Circuit Asymmetry for Direction Selectivity

Yonehara, Keisuke; Fiscella, Michele; Drinnenberg, Antonia; Esposti, Federico; Trenholm, Stuart; Krol, Jacek; Franke, Felix; Scherf, Brigitte Gross; Kusnyerik, Akos; Müller, Jan; Szabo, Arnold; Jüttner, Josephine; Cordoba, Francisco; Reddy, Ashrithpal Police; Németh, János; Nagy, Zoltán Zsolt; Munier, Francis; Hierlemann, Andreas; Roska, Botond

Congenital Nystagmus Gene FRMD7 Is Necessary for Establishing a Neuronal Circuit Asymmetry for Direction Selectivity Journal Article

Neuron, 89 (1), pp. 177-193, 2016, ISSN: 10974199.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Retina

2015

A method for electrophysiological characterization of hamster retinal ganglion cells using a high-density CMOS microelectrode array

Jones, Ian L; Russell, Thomas L; Farrow, Karl; Fiscella, Michele; Franke, Felix; Müller, Jan; Jäckel, David; Hierlemann, Andreas

A method for electrophysiological characterization of hamster retinal ganglion cells using a high-density CMOS microelectrode array Journal Article

Frontiers in Neuroscience, 9 , pp. 360, 2015, ISSN: 1662453X.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Retina

Visual coding with a population of direction-selective neurons

Fiscella, Michele; Franke, Felix; Farrow, Karl; Müller, Jan; Roska, Botond; Azeredo da Silveira, Rava ; Hierlemann, Andreas

Visual coding with a population of direction-selective neurons Journal Article

Journal of Neurophysiology, 114 (4), pp. 2485-2499, 2015, ISSN: 0022-3077.

Abstract | Links | BibTeX | Tags: Data Analysis, ETH-CMOS-MEA, Retina

High-resolution CMOS MEA platform to study neurons at subcellular, cellular, and network levels

Müller, Jan; Ballini, Marco; Livi, Paolo; Chen, Yihui; Radivojevic, Milos; Shadmani, Amir; Viswam, Vijay; Jones, Ian L; Fiscella, Michele; Diggelmann, Roland; Stettler, Alexander; Frey, Urs; Bakkum, Douglas J; Hierlemann, Andreas

High-resolution CMOS MEA platform to study neurons at subcellular, cellular, and network levels Journal Article

Lab Chip, 15 (13), pp. 2767-2780, 2015, ISSN: 1473-0197.

Abstract | Links | BibTeX | Tags: MaxOne, Neuronal Networks

A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture.

Krol, Jacek; Krol, Ilona; Alvarez, Claudia Patricia Patino; Fiscella, Michele; Hierlemann, Andreas; Roska, Botond; Filipowicz, Witold

A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. Journal Article

Nature Communications, 6 , pp. 7305, 2015, ISSN: 2041-1723.

Abstract | Links | BibTeX | Tags: MaxOne, Retina

Chronic Co-Variation of Neural Network Configuration and Activity in Mature Dissociated Cultures

Okawa, Satoru; Mita, Takeshi; Bakkum, Douglas J; Frey, Urs; Hierlemann, Andreas; Kanzaki, Ryohei; Takahashi, Hirokazu

Chronic Co-Variation of Neural Network Configuration and Activity in Mature Dissociated Cultures Journal Article

Electronics and Communications in Japan, 98 (5), pp. 34-42, 2015, ISSN: 1942-9541.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Neuronal Networks

Recording large extracellular spikes in microchannels along many axonal sites from individual neurons

Lewandowska, Marta K; Bakkum, Douglas J; Rompani, Santiago B; Hierlemann, Andreas

Recording large extracellular spikes in microchannels along many axonal sites from individual neurons Journal Article

PLoS ONE, 10 (3), pp. 1-24, 2015, ISSN: 19326203.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Neuronal Networks

Complexity Optimization and High-Throughput Low-Latency Hardware Implementation of a Multi-Electrode Spike-Sorting Algorithm

Dragas, Jelena; Jäckel, David; Hierlemann, Andreas; Franke, Felix

Complexity Optimization and High-Throughput Low-Latency Hardware Implementation of a Multi-Electrode Spike-Sorting Algorithm Journal Article

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 23 (2), pp. 149–158, 2015, ISSN: 15344320.

Abstract | Links | BibTeX | Tags: Spike Sorting

Revealing neuronal function through microelectrode array recordings

Obien, Marie Engelene J; Deligkaris, Kosmas; Bullmann, Torsten; Bakkum, Douglas J; Frey, Urs

Revealing neuronal function through microelectrode array recordings Journal Article

Frontiers in Neuroscience, 9 , pp. 423, 2015, ISSN: 1662453X.

Abstract | Links | BibTeX | Tags: MEA Technology, Review

2014

A 1024-channel CMOS microelectrode array with 26,400 electrodes for recording and stimulation of electrogenic cells in vitro

Ballini, Marco; Müller, Jan; Livi, Paolo; Chen, Yihui; Frey, Urs; Stettler, Alexander; Shadmani, Amir; Viswam, Vijay; Jones, Ian L; Jäckel, David; Radivojevic, Milos; Lewandowska, Marta K; Gong, Wei; Fiscella, Michele; Bakkum, Douglas J; Heer, Flavio; Hierlemann, Andreas

A 1024-channel CMOS microelectrode array with 26,400 electrodes for recording and stimulation of electrogenic cells in vitro Journal Article

IEEE Journal of Solid-State Circuits, 49 (11), pp. 2705-2719, 2014, ISSN: 00189200.

Abstract | Links | BibTeX | Tags: MaxOne, MEA Technology

Parameters for burst detection

Bakkum, Douglas J; Radivojevic, Milos; Frey, Urs; Franke, Felix; Hierlemann, Andreas; Takahashi, Hirokazu

Parameters for burst detection Journal Article

Frontiers in Computational Neuroscience, 7 , pp. 1-12, 2014, ISSN: 1662-5188.

Abstract | Links | BibTeX | Tags: Data Analysis, ETH-CMOS-MEA

2013

Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites

Bakkum, Douglas J; Frey, Urs; Radivojevic, Milos; Russell, Thomas L; Müller, Jan; Fiscella, Michele; Takahashi, Hirokazu; Hierlemann, Andreas

Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites Journal Article

Nature Communications, 4 , pp. 1-12, 2013, ISSN: 2041-1723.

Abstract | Links | BibTeX | Tags: Data Analysis, ETH-CMOS-MEA, Neuronal Networks

Sub-millisecond closed-loop feedback stimulation between arbitrary sets of individual neurons.

Müller, Jan; Bakkum, Douglas J; Hierlemann, Andreas

Sub-millisecond closed-loop feedback stimulation between arbitrary sets of individual neurons. Journal Article

Frontiers in Neural Circuits, 6 , pp. 121, 2013, ISSN: 1662-5110.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, MEA Technology, Neuronal Networks, Stimulation

2012

High-density microelectrode array recordings and real-time spike sorting for closed-loop experiments: an emerging technology to study neural plasticity

Franke, Felix; Jackel, David; Dragas, Jelena; Muller, Jan; Radivojevic, Milos; Bakkum, Douglas J; Hierlemann, Andreas

High-density microelectrode array recordings and real-time spike sorting for closed-loop experiments: an emerging technology to study neural plasticity Journal Article

Frontiers in Neural Circuits, 6 , pp. 105, 2012, ISSN: 1662-5110.

Abstract | Links | BibTeX | Tags: Neuronal Networks, Review, Spike Sorting

Recording from defined populations of retinal ganglion cells using a high-density CMOS-integrated microelectrode array with real-time switchable electrode selection

Fiscella, Michele; Farrow, Karl; Jones, Ian L; Jäckel, David; Müller, Jan; Frey, Urs; Bakkum, Douglas J; Hantz, Péter; Roska, Botond; Hierlemann, Andreas

Recording from defined populations of retinal ganglion cells using a high-density CMOS-integrated microelectrode array with real-time switchable electrode selection Journal Article

Journal of Neuroscience Methods, 211 (1), pp. 103-113, 2012, ISSN: 01650270.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Retina

Applicability of independent component analysis on high-density microelectrode array recordings

Jäckel, David; Frey, Urs; Fiscella, Michele; Franke, Felix; Hierlemann, Andreas

Applicability of independent component analysis on high-density microelectrode array recordings Journal Article

Journal of Neurophysiology, 108 (1), pp. 334-348, 2012, ISSN: 0022-3077.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, Spike Sorting

2011

The potential of microelectrode arrays and microelectronics for biomedical research and diagnostics

Jones, Ian L; Livi, Paolo; Lewandowska, Marta K; Fiscella, Michele; Roscic, Branka; Hierlemann, Andreas

The potential of microelectrode arrays and microelectronics for biomedical research and diagnostics Journal Article

Analytical and Bioanalytical Chemistry, 399 (7), pp. 2313-2329, 2011, ISSN: 1618-2650.

Abstract | Links | BibTeX | Tags: Review

Growing cells atop microelectronic chips: Interfacing electrogenic cells in vitro with CMOS-based microelectrode arrays

Hierlemann, Andreas; Frey, Urs; Hafizovic, Sadik; Heer, Flavio

Growing cells atop microelectronic chips: Interfacing electrogenic cells in vitro with CMOS-based microelectrode arrays Journal Article

Proceedings of the IEEE, 99 (2), pp. 252-284, 2011, ISSN: 00189219.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, MEA Technology, Review

2010

Compact voltage and current stimulation buffer for high-density microelectrode arrays

Livi, Paolo; Heer, Flavio; Frey, Urs; Bakkum, Douglas J; Hierlemann, Andreas

Compact voltage and current stimulation buffer for high-density microelectrode arrays Journal Article

IEEE Transactions on Biomedical Circuits and Systems, 4 (6), pp. 372-378, 2010, ISSN: 19324545.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, MEA Technology, Stimulation

Switch-matrix-based high-density microelectrode array in CMOS technology

Frey, Urs; Sedivy, Jan; Heer, Flavio; Pedron, Rene; Ballini, Marco; Müller, Jan; Bakkum, Douglas J; Hafizovic, Sadik; Faraci, Francesca D; Greve, Frauke; Kirstein, Kay Uwe; Hierlemann, Andreas

Switch-matrix-based high-density microelectrode array in CMOS technology Journal Article

IEEE Journal of Solid-State Circuits, 45 (2), pp. 467-482, 2010, ISSN: 00189200.

Abstract | Links | BibTeX | Tags: ETH-CMOS-MEA, MEA Technology

2009

Microelectronic system for high-resolution mapping of extracellular electric fields applied to brain slices

Frey, Urs; Egert, Ulrich; Heer, Flavio; Hafizovic, Sadik; Hierlemann, Andreas

Microelectronic system for high-resolution mapping of extracellular electric fields applied to brain slices Journal Article

Biosensors and Bioelectronics, 24 (7), pp. 2191-2198, 2009, ISSN: 09565663.

Abstract | Links | BibTeX | Tags: Brain Slice, ETH-CMOS-MEA

A synthetic mammalian electro-genetic transcription circuit

Weber, Wilfried; Luzi, Stefan; Karlsson, Maria; Sanchez-Bustamante, Carlota Diaz; Frey, Urs; Hierlemann, Andreas; Fussenegger, Martin

A synthetic mammalian electro-genetic transcription circuit Journal Article

Nucleic Acids Research, 37 (4), pp. 1-8, 2009, ISSN: 03051048.

Abstract | Links | BibTeX | Tags: Cardiomyocytes, ETH-CMOS-MEA

61 entries « 1 of 2 »

 

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