Discover all our events and activities that will be taking place during the ISSCR Annual Meeting 2023 in Boston from Wednesday June 14 – Saturday June 17!
Our team will be at ISSCR and would be happy to meet you!
Booth:
Visit us at booth #301 to learn more about our HD-MEA systems MaxOne and MaxTwo can further your research.
Innovation Showcase:
Friday June 16 11:30 – 12:30 | Room 253, Level 2
Title | Advanced Functional Characterization of iPSC-Derived 2D and 3D In Vitro Models at the Frontiers of Molecular Bioscience
Abstract | Two-dimensional (2D) or three-dimensional (3D) cell cultures are currently widely used in stem cell research. They aim to be as close to in vivo conditions to varying degrees, and, when derived from human induced pluripotent stem cells (iPSCs), provide a valuable alternative to animal models. Cell shape, differentiation, and proliferation, drug sensitivity and response to stimuli are among the characteristics guiding researchers to prefer one method to the other based on the scientific question and application. Considering that both 2D and 3D in vitro cellular models can serve as equally valuable tools to overcome the current barriers in stem cell research and further advance the field, we invited three speakers to spotlight on novel applications and methods to functionally characterize iPSC-derived cellular models. Scientific presentations will be followed by Q+A session and panel discussion to shine the light on current opinions about this controversial and highly relevant topic.
Speakers
Dr. Maria Sundberg Sahin Lab, Boston Children’s Hospital, Harvard Medical School, USA
Presentation Title:
Functional phenotyping of neurodevelopmental and psychiatric disorders with human iPSC-derived neurons
Dr. Jennifer Erwin Lieber Institute for Brain Development, USA
Presentation Title:
Integration of 3D human stem cell models derived from post-mortem tissue and statistical genomics to guide schizophrenia therapeutic development
Jay English Pak Lab, University of Massachusetts Amherst, USA
Presentation Title:
2D Human iPSC Models for Elucidating Synaptopathic Mechanisms of Neurodevelopmental Disorders
Session 4 | Modeling Development and Disease | Even
Poster Title
LABEL-FREE FUNCTIONAL CHARACTERIZATION OF IPSC-DERIVED NEURONS AT SUBCELLULAR RESOLUTION
Presenting
Silvia Oldani
Poster #906
Date and Time
Friday June 16 | 10:15 AM - 11:00 AM
Poster Session
Session 1 | New Technologies | Even
Poster Title
ENABLING NEXT GENERATION FUNCTIONAL CHARACTERIZATION OF HUMAN NEURAL ORGANOIDS
Presenting
Laura D’Ignazio
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