Marie Obien

Capture the activity of thousands of communicating neurons all at once

Latest Neurochip published in Nature Communications Today, a new generation of high-density microelectrode array (HD-MEA) technology has been published in Nature Communications (link). This publication not only demonstrates the excellent performance of the chip, but also describes the large-scale extraction of neuronal metrics, such as axonal conduction velocity, and includes impressive showcases of applications with various neuronal preparations. The developed versatile platform for label-free, live-cell electrical imaging will further accelerate drug discovery and basic research in the field of neuroscience.…

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MxW Monthly Must-Reads (01.2019)

Welcome to the first MxW Monthly Must-Reads (MMM) of 2019! This month’s selection of articles focuses on retina research. The retina, an extension of the brain and the first stage of visual input processing, extracts information about various features of visual stimuli, including size, contrast, colour, orientation and motion direction. With a diversity of neural subtypes both on the levels of local processing and downstream output via retinal ganglion cells, the retina is an amazing model for studying functional sub-circuits…

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MaxWell Monthly Must-Reads (June 2018)

June brings us to the fourth edition of our blog series, the MaxWell Monthly Must-Reads. This month’s selection of articles will focus on induced pluripotent stem cells or iPSCs. This technology, developed by researchers at Kyoto University lead by Dr. Shinya Yamanaka, allows adult cells to be genetically ‘reprogrammed’ to a stem cell-like state. Thus, it is possible to derive specific cell types from iPSCs, such as neurons and cardiomyocytes, providing a means to study human cells in-vitro. Increasingly, iPSCs are being used…

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MaxWell Monthly Must-Reads (May 2018)

Time goes by fast, and it is already time for the May edition of MaxWell Monthly Must-Reads. This month’s blog series will focus on a well-studied region of the brain, the Hippocampus. We picked this topic for this month as the hippocampus is an interesting model system for studying mechanisms involved in memory storage. MaxOne provides a high-resolution recording and stimulation platform for investigating single cells and networks in hippocampal slices and cell cultures. This month’s MMM includes a methods article utilizing our…

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MaxWell Monthly Must-Reads (April 2018)

After last month’s successful launch , it is finally time for the April edition of MaxWell Monthly Must-Reads. This month’s blog series will focus on Neuronal Excitability. The topic plays a key role in understanding how neurons encode and transmit information. At MaxWell Biosystems, we aim to develop assays for characterizing neuronal excitability, both in healthy and disease conditions. For this month’s MMM, we include recent studies on different factors that regulate excitability of neurons, such as ion channels, calcium signaling, and…

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