An Implantable Biohybrid Neural Interface Toward Synaptic Deep Brain Stimulation
Sensory nerve regrowth is often limited by the inhibitory nature of the extracellular matrix, which restricts axonal regeneration. Although cortical and deep brain stimulation offer potential therapeutic approaches, their effectiveness in sensory restoration is hindered by challenges in spatial resolution, cell specificity, and accessibility. In a recent study published in Advanced Functional Materials, researchers introduced an implantable biohybrid neural interface that integrates neural spheroids with a stretchable stimulation array and a microfluidic axon guidance system…