Applications

MaxWell Monthly Must-Reads | World Alzheimer’s Day

September 21, 2023
Patricia Valerio
Applications, Blog, MaxWell Monthly Must-Reads

On this World Alzheimer’s Day, we are raising awareness on the ongoing research that seeks to unravel the mysteries behind Alzheimer’s disease. Join us in celebrating the incredible advances in this research field and outstanding scientific tools supporting discoveries on risk factors and underlying mechanisms, as well as potential treatments for Alzheimer’s. Alzheimer’s disease is a progressive neurodegenerative disorder characterized by a decline in cognitive function and memory. Symptoms can include memory loss, confusion, language impairment, and changes in behavior…

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Interview with Brett Kagan – Cortical Labs

June 12, 2023
Patricia Valerio
Applications, Blog, MaxOne

MxW Interview with Brett Kagan Cortical Labs, Melbourne, Australia Recently, we had the pleasure of having Dr. Brett Kagan from Cortical Labs visiting us here in the MaxWell Biosystems HQ in Zurich and hosting an exciting seminar on their recent work and progress. Dr. Brett Kagan’s latest work on “training neural networks to play Pong using HD-MEAs”, published in Neuron (Kagan et al, Neuron, 2022), became viral last year, and we had the opportunity to learn more about this study,…

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MaxWell Monthly Must-Reads | World Organoid Research Day

March 22, 2023
Patricia Valerio
Blog, MaxWell Monthly Must-Reads, Organoids

  Today is World Organoid Research Day! Let’s celebrate the incredible advances being made in this fascinating and yet rapidly evolving field of research by raising awareness on the potential of organoids in advancing biomedical research, drug discovery, regenerative medicine, modeling complex diseases, personalized medicine, reducing animal testing, and advancing stem cell research. Grown from human stem cells, organoids are miniaturized three-dimensional structures that closely resemble the architecture and function of real human organs, providing a more complex and comprehensive…

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Join the Conversation with Prof. Kenneth S. Kosik and Dr. Tal Sharf

December 24, 2021
Marie Obien
Applications, Blog, Featured, MaxOne, Organoids, Publications

Interview and Featured Publication Join the Conversation with Prof. Kenneth Kosik and Dr. Tal Sharf Recently, Dr. Tal Sharf, Prof. Kenneth S. Kosik and colleagues released a pre-print on their novel work entitled, “Human brain organoid networks”, currently under revision. Aiming to explore the physiological behavior of neuronal circuits within organoids, this work demonstrates that human brain organoids have self-organized neuronal assemblies of sufficient size, cellular orientation, and functional connectivity to co-activate and generate field potentials from their collective transmembrane…

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HD-MEAs play a role in the functional characterization of human iPSC-derived dopaminergic neurons

June 22, 2021
Patricia Valerio
Blog, iPSC, MaxOne, News, Publications

Maria Sundberg from the Boston Children’s Hospital, Harvard Medical School, and colleagues, recently reported in Nature Communications a study on the reciprocal copy number variations (CNVs) of 16p11.2 gene region, associated with a wide spectrum of neuropsychiatric and neurodevelopmental disorders. For the functional analysis of the developing iPSC-derived dopaminergic (DA) neuron network, complementary-metal-oxide-semiconductor (CMOS)-based high-density microelectrode arrays (HD-MEAs), MaxOne System by MaxWell Biosystems was extensively used. 16p.11.2 Reciprocal copy number variations (CNVs) in neuropsychiatric disorders 16p.11.2 CNVs have been implicated in…

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